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Table 3 Ub-proteasome pathway deletion mutants evaluated for cisplatin sensitivity: S. cerevisiae and human homolog/ortholog genes

From: Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast

 

Homolog/Ortholog

Annotation

S. cerevisiae

Human

dph1

DSK2

-

ubp2

UBP2

-

pcu3

-

-

cul3

UFD4

-

UB-lig (E3)

-

-

ucp2, ubp14

UBP14

-

ubp16

UBP10

-

ubp3

YER151C

-

ubr1

UBR1/PTR1/UBR2

-

mug30

HUL4

-

UB-metalloprotease

-

-

uch1

YUH1

UCHL3

UB family...

-

-

ubp22/ubp15

UPB15

USP7

ubc13/spu13

UBC13

UBC13/UBE2N

ubc6

UBC6

UBE2J2

ubc14

-

-

ubp8

UBP8

USP22

Ub family...

-

-

pre6

PRE6

PSMA8

uch2

YUH1

UCHL3

bag102 / bag1-b

SNL1

-

UB-lig (E3)

-

-

ulp1 (SUMO-deconj)

ULP1

SENP8

brl1

BRE1

-

UB-lig (E3)

SAN1

-

20S (sub.β7)

PRE4

PSMB4

dma1

DMA1

-

ubi3

RPS31

-

ufd2

UFD2

UBE4B

ubp11

-

-

UB-lig (E3)

-

-

ubp7

UBP7

USP45

let1/rpt6 (19S)

RPT6

PSMC5

lub1

DOA1

PLAA

ubr11

-

UBR2

ubc16

-

-

cut8

-

-

ubp4

DOA4/UBP4

-

pep3

-

VPS18

pub3

RSP5

NEDD4

pub2

RSP5

NEDD4

rpt4

RPT4

PSMC6

ubp6

UBP6

USP14

atg7

ATG7

ATG7

ubc1

UBC1

UBE2K

pmt3

SMT3

SUMO