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Table 6 Putative P. larvae based on matches to conserved domains.

From: Updated genome assembly and annotation of Paenibacillus larvae, the agent of American foulbrood disease of honey bees

Protein (E-value)

Domain, functional information from CDD

EFX44344 (2E-37)

AmpS [COG2309]: Leucyl aminopeptidase (aminopeptidase T)

EFX45451 (6E-13)

APP-like [cd01092]: Prolidase and Aminopeptidase P

EFX47002 (0)

clpC [CHL00095]: Clp protease ATP binding subunit

EFX46058 (4E-5)

ClpP [COG0740]: Protease subunit of ATP-dependent Clp proteases

EFX44161 (1E-85),

EFX45289 (1E-82)

clpP [PRK00277]: Clp protease proteolytic subunit

EFX45288 (7E-170)

clpX [PRK05342]: Clp protease ATP-binding subunit

EFX45551 (7E-82),

COG0826 [COG0826]: Collagenase and related proteases

EFX45550 (4E-48),

 

EFX45481 (3E-19),

 

EFX44736 (1E-28)

 

EFX44399 (9E-8*)

COG1310 [COG1310]: Predicted metal-dependent protease of the PAD1/JAB1 superfamily

EFX46420 (8E-149)

COG2317 [COG2317]: Zn-dependent carboxypeptidase

EFX44401 (9E-45)

COG2738 [COG2738]: Predicted Zn-dependent protease

EFX44533 (2E-9),

EFX45796 (2E-9)

COG2856 [COG2856]: Predicted Zn peptidase

EFX46883 (2E-31)

COG3740 [COG3740]: Phage head maturation protease

EFX45850 (6E-11)

COG4942 [COG4942]: Membrane-bound metallopeptidase

EFX46250 (1E-34),

EFX44926 (2E-64)

degP_htrA_DO [TIGR02037]: periplasmic serine protease, Do/DeqQ family

EFX47184 (5E-45)

DegQ [COG0265]: Trypsin-like serine proteases, typically periplasmic

EFX46573 (5E-91),

FtsH_fam [TIGR01241]: ATP-dependent metalloprotease FtsH

EFX44535 (5E-20*),

 

EFX44172 (3E-17*)

 

EFX47022 (0)

HflB [COG0465]: ATP-dependent Zn proteases

EFX45319 (1E-36*),

EFX44073 (5E-8*)

HflC [COG0330]: membrane protease subunits, stomatin/prohibitin homologs

EFX46036 (4E-157)

HslU [COG1220]: ATP-dependent protease HslVU (ClpYQ), ATPase subunit

EFX46037 (8E-65)

HslV [COG5405]: ATP-dependent protease HslVU (ClpYQ), peptidase subunit

EFX43995 (2E-97),

LasB [COG3227]: Zinc metalloprotease (elastase)

EFX45639 (1E-78),

 

EFX45177 (9E-58)

 

EFX45284 (0)

Lon [COG0466]: ATP-dependent Lon protease

EFX43687 (8E-131)

M3_fam_3 [TIGR02290]: oligoendopeptidase, pepF/M3 family

EFX44444 (2E-74)

M14_Endopeptidase_I [cd06229]: Peptidase M14-like domain of Gamma-D-glutamyl-L-diamino acid endopeptidase 1

EFX44181 (2E-45)

MrcA [COG5009]: Membrane carboxypeptidase/penicillin-binding protein

EFX45553 (4E-10*),

MrcB [COG0744]: Membrane carboxypeptidase (penicillin-binding protein)

EFX46407 (3E-97*),

 

EFX44298 (3E-75*),

 

EFX46175 (2E-122*),

 

EFX44515 (1E-12*),

 

EFX44516 (4E-11*)

 

EFX45371 (7E-9), EFX45028 (2E-7), EFX45493 (4E-25)

NlpD [COG0739]: Membrane proteins related to metalloendopeptidases

EFX44427 (8E-144)

pepF [TIGR00181]: oligoendopeptidase F

EFX46173 (4E-9)

PepN [COG0308]: Aminopeptidase N

EFX45105 (1E-66)

PepP [COG0006]: Xaa-Pro aminopeptidase

EFX47190 (3E-18)

Peptidase_M23 [pfam01551]: Peptidase family M23

EFX46425 (8E-126)

Peptidase_M6 [pfam05547]: Immune inhibitor A peptidase M6, a metallopeptidase from Bacillus thuringiensis that cleaves host antibacterial proteins

EFX47085 (4E-29)

Peptidase_M9_N [pfam08453]: Peptidase family M9 N-terminal

EFX46343 (8E-6*)

Peptidase_S24 [pfam00717]: Peptidase S24-like

EFX43847 (9E-13)

Peptidase_S41_CPP [cd07560]: C-terminal processing peptidase; serine protease family S41

EFX43943 (3E-27*)

Peptidase_S66 [pfam02016]: LD-carboxypeptidase; this cleaves the bond between an L- and a D-amino acid

EFX45480 (6E-38), EFX45479 (2E-8)

Peptidase_U32 [pfam01136]: Peptidase family U32

EFX43960 (8E-78),

EFX45983 (2E-59)

Peptidases_S8_11 [cd04843]: Peptidase S8 family domain, uncharacterized subfamily 11

EFX46806 (8E-36)

Peptidases_S8_Lantibiotic_specific_protease [cd07482]: Peptidase S8 family domain in Lantiobiotic (lanthionine-containing antibiotics) specific proteases

EFX44534 (5E-26), EFX45795 (1E-20*), EFX44174 (8E-25)

Peptidases_S8_Subtilisin_like_2 [cd04847]: Peptidase S8 family domain in Subtilisin-like proteins

EFX45938 (8E-46), EFX45020 (3E-62), EFX46180 (2E-50), EFX45070 (2E-20)

Peptidases_S8_Subtilisin_subset [cd07477]: Peptidase S8 family domain in Subtilisin proteins

EFX44839 (5E-67),

EFX44567 (5E-47),

EFX44567 (4E-55)

Peptidases_S8_Thermitase_like [cd07484]: Peptidase S8 family domain in Thermitase-like proteins

EFX47149 (7E-172)

peptidase-T [TIGR01882]: peptidase T

EFX45664 (5E-87)

PepT-like [TIGR01883]: peptidase T-like protein

EFX46054 (6E-33),

EFX46055 (2E-7),

EFX46066 (2E-67)

PqqL [COG0612]: Predicted Zn-dependent peptidases

EFX45492 (3E-73)

prc [TIGR00225]: C-terminal peptidase (prc)

EFX44827 (3E-16*)

PRK00016 [PRK00016]: putative metalloprotease

EFX44779 (1E-110)

PRK02858 [PRK02858]: germination protease

EFX45078 (5E-118)

PRK07318 [PRK07318]: dipeptidase PepV

EFX44480 (4E-11*)

PRK08554 [PRK08554]: peptidase

EFX45711 (2E-73)

PRK09795 [PRK09795]: aminopeptidase

EFX45631 (4E-24*),

EFX44757 (1E-22*)

PRK13914 [PRK13914]: invasion associated secreted endopeptidase

EFX44490 (3E-22*)

PRK14791 [PRK14791]: lipoprotein signal peptidase

EFX46689 (1E-42)

S14_ClpP_1 [cd07016]: Caseinolytic protease (ClpP)

EFX44792 (2E-28)

S2P-M50_like_1 [cd06158]: Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms

EFX44503 (2E-42)

spore_II_GA [TIGR02854]: sigma-E processing peptidase SpoIIGA

EFX45851 (1E-12)

S2P-M50_SpoIVFB [cd06161]: SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP)

EFX47001 (2E-8*)

spore_lon_C[TIGR02903]: ATP-dependent protease, Lon family

EFX45285 (0)

spore_lonB [TIGR02902]: ATP-dependent protease LonB

EFX46081 (7E-45)

TIGR00054 [TIGR00054]: RIP metalloprotease RseP

EFX44693 (1E-61)

trio_M42_hydro [TIGR03106]: hydrolase, peptidase M42 family

  1. *the listed match is not the one with the lowest E-value; it is displayed because it is the most informative