Figure 3

Non-conserved cell cycle motifs are more nucleosome-occupied. A. Genes containing the SWI4 DNA sequence binding consensus [AGT]ACGCG[AT][ACG]A in the upstream region in S. bayanus were divided into two categories, depending on motif occurrence in the orthologous upstream region in S. cerevisiae. The genes without the SWI4 consensus motif in S. cerevisiae (black line, C, arrow points to motif positions) tend to be more nucleosome-occupied on the motif position than the genes with conserved SWI4 motifs (blue line, B). D. The MBP1 DNA sequence consensus [AGT][AT]CGCGT[CT][AGT] observed in S. bayanus (similar to the MBP1 motif identified in S. cerevisiae) was divided into two categories: conserved (E) versus not present in S. bayanus (F). The genes with an MBP1 motif present in only S. cerevisiae (black line) are consistently more nucleosome occupied compared to the genes for which MBP1 binding sites are conserved in both species (blue line).