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Figure 4 | BMC Genomics

Figure 4

From: Ortho2ExpressMatrix—a web server that interprets cross-species gene expression data by gene family information

Figure 4

Ortho2ExpressMatrix case study B. PIK3CD data were extracted from two different public resources, confer Figure 3. This Figure shows the respective Ensembl Family ENSFM00520000517795 for PIK3 genes (alpha to delta subunits of the catalytic phosphoinositide-3-kinase) of human and mouse; the reader should note that the organism configuration is mutual to Figure 3. Explanations in numbers 1, 2, 3, 5 and 6 correspond to the numbers in Figure 3. Pre-selection such as 'lower differential expression parallel in both organisms' enforces the automatic check-in of the HTML check boxes and the mouse-over explanation as shown (the lower differential expression of PIK3CD in both organisms as reaction on RUNX1 silencing/depletion is the focus of the original literature, see text). This Figure shows a manually reduced pre-selection that shall indicate that there are now three proteins (ASIs) of the human gene PIK3CD and six proteins (ASIs) of the mouse gene Pik3cd selected for the Table output display (number 4; see also 'Utility/Table output'). The statistical analysis (number 7) shows significances given by down-regulated probe sets and calculated by over-representation analysis p-values in mouse and human.

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