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Table 1 Region of difference (RD) profiles in BCG Mexico strains.

From: Genomic and proteomic analyses of Mycobacterium bovis BCG Mexico 1931 reveal a diverse immunogenic repertoire against tuberculosis infection

BCG Profile of regions of difference
Substrains RD1 RD2 RD8 RD14 RD16 RD18 RDD/G IS6110 DU2
Mexico
seed lot 1931
- - + + + - + + IV
Phipps - - + + + - + + IV
Tice - - + + + - + + IV
Mexico
seed lot 1988
- - + + + + - + III
Mexico
vaccine 1997
- - + + + + - + III
Danish 1331 - - + + + + - + III
  1. The symbol (-) indicates the loss of a region in the genome of a given strain, whereas the symbol (+) indicates the presence of the region. RD = region of difference; IS6110 = insertion sequence IS6110 (presence of a single copy); DU = tandem duplication.