Figure 4
From: Transcriptional signatures of regulatory and toxic responses to benzo-[a]-pyrene exposure
Enrichment of each cluster for Ahr mutant-perturbed genes. Using data from previous Ahr mutant studies [7, 19], we assessed whether each cluster was enriched (relative to the other clusters) for genes perturbed by an Ahr mutation. Only genes not used in the training of the classifier were used in the calculation of enrichment. Cluster 3 was highly enriched for perturbed genes, suggesting that it is enriched for Ahr targets.