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Table 1 Univariate and multivariate Cox regression analysis for progression free survival

From: Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis

  

Univariate analysis

Multivariate analysis

Factor

Patients (n = 248)

HR

95% CI

p-val

HR

95% CI

p-val

TCF12 expression

       

   Neg/weak

200

1

Reference

 

1

Reference

 

   Strong

48

2.03

1.03-4.01

0.04

2.24

1.17-4.73

0.02

Sex

       

   Female

120

1

Reference

    

   Male

128

1.82

0.95-3.51

0.07

   

Age at surgery

       

   < = 71

128

1

Reference

    

   >71

120

1.26

0.67-2.38

0.46

   

Tumour location

       

   Colon

158

1

Reference

    

   Rectum

90

1.11

0.57-2.08

0.80

   

T-stage

       

   pT3

226

1

Reference

    

   pT4

22

0.81

0.27-2.80

0.74

   

Tumor sizea

       

   <50 mm

135

1

Reference

    

   >50 mm

112

0.70

0.35-1.30

0.24

   

Histological typea

       

   Adenocarcinoma

217

1

Reference

    

   Mucinous

27

1.18

0.46-4.88

0.50

   

Number of nodesa

       

   < = 10

119

1

Reference

 

1

Reference

 

   >10

119

2.01

1.00-4.04

0.05

2.10

1.00-4.03

0.05

  1. HR = hazard ratio; 95% CI = 95% confidence interval.
  2. aPatients with missing values were excluded from the analysis.
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BMC Genomics

ISSN: 1471-2164

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