Table 2 List of top 50 genes significantly differentially regulated in the skeletal muscle based on fold difference (t-test).
Gene Symbol | 2Way ANOVA P value | Fold Change in Skeletal muscle, Welch t-test | Regulation in LBW | Fold change Liver, Welch t-test | Regulation in LBW | Fold change in Cords, Welch t-test | Regulation in LBW | Gene name |
|---|---|---|---|---|---|---|---|---|
XM_116936 | 0.017913306 | 10.054285 | up | 1.080386 | up | 2.185324 | up | PREDICTED: Homo sapiens similar to RIKEN cDNA 4832428D23 gene (LOC196541) mRNA [XM_116936] |
XM_056254 | 0.021895792 | 9.569201 | up | 2.09208 | down | 1.391897 | up | PREDICTED: Homo sapiens heparan sulfate (glucosamine) 3-O-sulfotransferase 4 (HS3ST4) mRNA [XM_056254] |
C5orf23 | 0.01475329 | 6.0808635 | up | 1.072585 | up | 1.301361 | up | Homo sapiens chromosome 5 open reading frame 23 (C5orf23), mRNA [NM_024563] |
PASK | 0.03426426 | 5.977056 | up | 2.995584 | up | 19.17474 | up | Homo sapiens PAS domain containing serine/threonine kinase (PASK), mRNA [NM_015148] |
WDR8 | 0.004681234 | 5.6804295 | down | 2.978104 | down | 8.061375 | down | Homo sapiens WD repeat domain 8 (WDR8), mRNA [NM_017818] |
ADK | 1.63E-04 | 5.639505 | down | 1.368648 | down | 9.386349 | down | Homo sapiens adenosine kinase (ADK), transcript variant ADK-short, mRNA [NM_001123] |
APOBEC3G | 0.040698703 | 4.8567457 | down | 1.669566 | down | 1.105857 | down | Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G (APOBEC3G), mRNA [NM_021822] |
CCL2 | 0.002121243 | 4.757898 | down | 1.287543 | down | 2.895307 | down | Homo sapiens chemokine (C-C motif) ligand 2 (CCL2), mRNA [NM_002982] |
A_01_P013390 | 0.029869065 | 4.6248507 | down | 1.099004 | down | 1.527467 | down | Â |
BC044226 | 0.04677891 | 4.3998837 | down | 1.966762 | down | 1.502299 | down | Homo sapiens myosin binding protein H, mRNA [BC044226] |
CCL11 | 0.008992519 | 4.050988 | down | 3.178148 | down | 1.002582 | up | Homo sapiens chemokine (C-C motif) ligand 11 (CCL11), mRNA [NM_002986] |
POU4F3 | 0.02459994 | 3.8642302 | up | 1.615214 | up | 1.991698 | down | Homo sapiens POU domain, class 4, transcription factor 3 (POU4F3), mRNA [NM_002700] |
XR_011794 | 0.010519872 | 3.7855186 | up | 3.637105 | up | 2.76764 | up | PREDICTED: Macaca mulatta similar to poly(A)-specific ribonuclease (PARN)-like domain containing 1 (LOC707835), mRNA [XR_011794] |
H1FOO | 0.011109326 | 3.7804163 | up | 1.404401 | up | 1.449255 | down | Homo sapiens H1 histone family, member O, oocyte-specific (H1FOO), mRNA [NM_153833] |
C17orf75 | 0.001362531 | 3.7583363 | down | 3.447702 | down | 1.443745 | down | Homo sapiens chromosome 17 open reading frame 75 (C17orf75), mRNA [NM_022344] |
RNF216 | 0.001650785 | 3.7307158 | down | 1.504036 | down | 6.793567 | down | Homo sapiens TRIAD3 protein (TRIAD3), transcript variant 1, mRNA [NM_207111] |
GTSF1 | 0.017040279 | 3.6632807 | up | 4.653995 | up | 2.487166 | up | Homo sapiens family with sequence similarity 112, member B (FAM112B), mRNA [NM_144594] |
C13orf33 | 0.006214988 | 3.5870998 | down | 2.664488 | down | 1.061963 | up | Homo sapiens chromosome 13 open reading frame 33 (C13orf33), mRNA [NM_032849] |
CA2 | 0.033340864 | 3.5736616 | down | 3.483002 | down | 1.194329 | up | Homo sapiens carbonic anhydrase II (CA2), mRNA [NM_000067] |
CO645773 | 0.03704907 | 3.5384166 | down | 2.022003 | down | 1.474969 | down | ILLUMIGEN_MCQ_30118 Katze_MMPB Macaca mulatta cDNA clone IBIUW:22572 5' similar to Bases 1 to 42 highly similar to human RARRES3 (Hs.17466), mRNA sequence [CO645773] |
MYST3 | 0.013409907 | 3.3029778 | up | 2.827006 | up | 1.403819 | up | Homo sapiens MYST histone acetyltransferase (monocytic leukemia) 3 (MYST3), mRNA [NM_006766] |
NM_000977 | 0.008561992 | 3.2655115 | up | 2.138359 | up | 2.014805 | up | Homo sapiens ribosomal protein L13 (RPL13), transcript variant 1, mRNA. [NM_000977] |
XR_014265 | 0.001382546 | 3.2319098 | down | 1.270026 | down | 2.168579 | down | PREDICTED: Macaca mulatta hypothetical protein LOC716045 (LOC716045), mRNA [XR_014265] |
NM_001004685 | 0.043442905 | 3.1747854 | up | 1.353824 | up | 1.407273 | down | Homo sapiens olfactory receptor, family 2, subfamily F, member 2 (OR2F2), mRNA. [NM_001004685] |
XR_014204 | 0.029225934 | 3.167453 | down | 3.849135 | down | 1.084816 | up | PREDICTED: Macaca mulatta hypothetical protein LOC719546 (LOC719546), mRNA [XR_014204] |
DARS | 3.99E-05 | 3.1527941 | down | 1.10567 | down | 12.63266 | down | Homo sapiens aspartyl-tRNA synthetase (DARS), mRNA [NM_001349] |
GYLTL1B | 9.45E-04 | 3.143812 | up | 1.169517 | up | 3.19979 | up | Homo sapiens glycosyltransferase-like 1B (GYLTL1B), mRNA [NM_152312] |
CNNM2 | 1.94E-04 | 3.1423542 | up | 1.00608 | down | 1.785853 | up | Homo sapiens cyclin M2 (CNNM2), transcript variant 1, mRNA [NM_017649] |
C20orf26 | 0.023210809 | 3.1168563 | up | 1.353857 | up | 1.414684 | up | Homo sapiens chromosome 20 open reading frame 26 (C20orf26), mRNA [NM_015585] |
SLC26A9 | 0.042099766 | 3.0884879 | up | 2.137558 | up | 1.776504 | up | Homo sapiens solute carrier family 26, member 9 (SLC26A9), transcript variant 1, mRNA [NM_052934] |
SEC14L3 | 0.025527291 | 3.0402198 | up | 1.787294 | up | 1.547541 | down | Homo sapiens SEC14-like 3 (S. cerevisiae) (SEC14L3), mRNA [NM_174975] |
TMEM20 | 0.001055841 | 2.9346027 | down | 1.821723 | down | 1.558415 | down | Homo sapiens transmembrane protein 20 (TMEM20), mRNA [NM_153226] |
UHRF1 | 0.042854026 | 2.9323897 | down | 1.272487 | down | 1.455897 | down | Homo sapiens ubiquitin-like, containing PHD and RING finger domains, 1 (UHRF1), transcript variant 2, mRNA [NM_013282] |
CST9L | 0.008572864 | 2.9286344 | up | 1.46455 | up | 1.695363 | down | Homo sapiens cystatin 9-like (mouse) (CST9L), mRNA [NM_080610] |
C2 | 0.005425731 | 2.906241 | down | 1.470166 | down | 1.228973 | up | Homo sapiens complement component 2 (C2), mRNA [NM_000063] |
C7orf62 | 0.03373279 | 2.8281868 | up | 1.466387 | up | 1.326441 | down | Homo sapiens hypothetical protein MGC26647 (MGC26647), mRNA [NM_152706] |
HOXB13 | 0.008404698 | 2.822795 | up | 1.530259 | up | 1.061908 | down | Homo sapiens homeobox B13 (HOXB13), mRNA [NM_006361] |
ANLN | 0.026928915 | 2.8110342 | down | 1.205709 | down | 1.210447 | down | Homo sapiens anillin, actin binding protein (ANLN), mRNA [NM_018685] |
TMEM45B | 0.02836952 | 2.789488 | up | 1.108079 | up | 1.434473 | up | Homo sapiens transmembrane protein 45B (TMEM45B), mRNA [NM_138788] |
COL8A2 | 0.029133584 | 2.7760508 | down | 1.111961 | down | 2.334076 | down | Homo sapiens collagen, type VIII, alpha 2 (COL8A2), mRNA [NM_005202] |
IL15RA | 3.56E-05 | 2.7710447 | down | 2.542192 | down | 5.776398 | down | Homo sapiens interleukin 15 receptor, alpha (IL15RA), transcript variant 2, mRNA [NM_172200] |
AY937248 | 0.002621024 | 2.7557867 | up | 1.074139 | down | 2.046131 | up | Macaca mulatta placental protein 14 mRNA, complete cds [AY937248] |
SCN3B | 0.00199475 | 2.7342772 | up | 1.566765 | up | 1.26591 | up | Homo sapiens sodium channel, voltage-gated, type III, beta (SCN3B), transcript variant 1, mRNA [NM_018400] |
TRIM6 | 0.005424626 | 2.7181938 | up | 1.451755 | up | 1.960095 | up | Homo sapiens tripartite motif-containing 6 (TRIM6), transcript variant 1, mRNA [NM_001003818] |
TNS4 | 0.041628703 | 2.7158492 | up | 1.315606 | up | 1.297834 | down | Homo sapiens tensin 4 (TNS4), mRNA [NM_032865] |
PDE1C | 0.026903268 | 2.6685586 | up | 1.596604 | up | 1.15087 | down | Homo sapiens phosphodiesterase 1C, calmodulin-dependent 70kDa (PDE1C), mRNA [NM_005020] |
S100A4 | 0.01836204 | 2.656307 | down | 1.047433 | down | 2.01034 | down | Homo sapiens S100 calcium binding protein A4 (S100A4), transcript variant 1, mRNA [NM_002961] |
AADACL1 | 0.017924123 | 2.6216743 | down | 1.119603 | down | 1.47176 | down | Homo sapiens arylacetamide deacetylase-like 1 (AADACL1), mRNA [NM_020792] |
XR_011345 | 0.029255124 | 2.6165082 | up | 1.450092 | up | 1.492756 | down | PREDICTED: Macaca mulatta similar to otoancorin isoform 1 (LOC699600), mRNA [XR_011345] |
FN1 | 0.02028952 | 2.6025481 | down | 1.05622 | down | 1.051482 | down | Homo sapiens fibronectin 1 (FN1), transcript variant 1, mRNA [NM_212482] |
SP7 | 3.05E-04 | 2.5985072 | up | 1.616763 | up | 1.088733 | down | Homo sapiens Sp7 transcription factor (SP7), mRNA [NM_152860] |