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Table 4 Top 50 genes significantly differentially regulated in cord based on fold difference (t-test).

From: Gene expression profiling in the Cynomolgus macaque Macaca fascicularis shows variation within the normal birth range

Gene Symbol 2Way ANOVA P value Fold Change in cord, Welch t-test Regulation in LBW Fold change skeletal tissue, Welch t-test Regulation in LBW Fold change in liver, Regulation in LBW Gene name
ATP5F1 0.003504217 29.998667 down 1.850386 down 1.153583 down Homo sapiens ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 (ATP5F1), nuclear gene encoding mitochondrial protein, mRNA [NM_001688]
EHHADH 3.25E-05 29.713446 down 1.004504 up 1.027032 down Homo sapiens enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase (EHHADH), mRNA [NM_001966]
CNPY2 6.12E-05 24.275322 down 2.033511 down 1.345912 down Homo sapiens transmembrane protein 4 (TMEM4), mRNA [NM_014255]
IMMP1L 5.31E-04 21.21959 down 1.067236 down 1.052987 up Homo sapiens IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) (IMMP1L), mRNA [NM_144981]
GNL2 0.008845676 19.523186 down 1.389994 down 1.352022 up Homo sapiens guanine nucleotide binding protein-like 2 (nucleolar) (GNL2), mRNA [NM_013285]
HRSP12 0.010644738 19.35189 down 1.121147 up 1.013192 up Homo sapiens heat-responsive protein 12 (HRSP12), mRNA [NM_005836]
CN643639 2.57E-05 19.177528 down 1.710693 down 1.132373 up ILLUMIGEN_MCQ_8235 Katze_MMBR Macaca mulatta cDNA clone IBIUW:3333 5' similar to Bases 1 to 682 highly similar to human Unigene Hs.513885, mRNA sequence [CN643639]
PASK 0.03426426 19.17474 up 5.977056 up 2.995584 up Homo sapiens PAS domain containing serine/threonine kinase (PASK), mRNA [NM_015148]
NDUFC1 1.93E-04 18.786453 down 1.418954 down 1.095977 up Homo sapiens NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6 kDa (NDUFC1), mRNA [NM_002494]
BNIP3L 3.67E-05 18.46857 down 2.523903 down 1.123252 down Homo sapiens BCL2/adenovirus E1B 19 kDa interacting protein 3-like (BNIP3L), mRNA [NM_004331]
GALE 0.004030123 18.304993 down 1.591229 up 1.378757 down Homo sapiens UDP-galactose-4-epimerase (GALE), transcript variant 1, mRNA [NM_000403]
XM_371837 2.06E-06 18.251152 down 1.76245 down 1.15429 down PREDICTED: Homo sapiens similar to oxidoreductase UCPA (LOC389416), mRNA [XM_371837]
OSTCL 9.90E-05 17.57389 down 1.173702 down 1.075778 down Homo sapiens similar to RIKEN cDNA 2310008M10 (LOC202459), mRNA [NM_145303]
WDR75 7.83E-05 17.02899 down 2.353145 down 1.037028 down Homo sapiens WD repeat domain 75 (WDR75), mRNA [NM_032168]
SMPDL3A 1.25E-05 16.127317 down 1.290077 down 1.780315 down Homo sapiens sphingomyelin phosphodiesterase, acid-like 3A (SMPDL3A), mRNA [NM_006714]
LIN7C 6.29E-04 15.929515 down 1.429568 down 1.006664 down Homo sapiens lin-7 homolog C (C. elegans) (LIN7C), mRNA [NM_018362]
COX7B 8.03E-06 15.9135065 down 1.283232 down 1.138854 up Homo sapiens cytochrome c oxidase subunit VIIb (COX7B), nuclear gene encoding mitochondrial protein, mRNA [NM_001866]
MRPL1 1.35E-06 15.901582 down 1.776047 down 1.05264 up Homo sapiens mitochondrial ribosomal protein L1 (MRPL1), nuclear gene encoding mitochondrial protein, mRNA [NM_020236]
NPM3 3.58E-04 15.357531 down 1.39378 down 1.314134 up Homo sapiens nucleophosmin/nucleoplasmin, 3 (NPM3), mRNA [NM_006993]
RNF126 4.43E-04 15.14725 down 1.165075 down 1.084156 down Homo sapiens ring finger protein 126 (RNF126), transcript variant 2, mRNA [NM_194460]
ATG4C 1.86E-06 14.422242 down 1.01449 down 1.571663 down Homo sapiens ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 7, mRNA [NM_032852]
ACMSD 2.00E-04 14.3137 down 1.121731 up 1.098467 down Homo sapiens aminocarboxymuconate semialdehyde decarboxylase (ACMSD), mRNA [NM_138326]
WASF3 0.0026955 14.211387 down 1.134297 down 1.574282 up Homo sapiens WAS protein family, member 3 (WASF3), mRNA [NM_006646]
F13B 1.26E-05 13.94526 down 1.052562 down 1.02993 down Homo sapiens coagulation factor XIII, B polypeptide (F13B), mRNA [NM_001994]
HNRNPA1L2 0.007305239 13.879195 down 1.288451 up 1.062584 down Homo sapiens heterogeneous nuclear ribonucleoprotein A1-like (LOC144983), transcript variant 1, mRNA [NM_001011724]
XR_011737 0.001940294 13.592515 down 1.736661 down 1.168041 up PREDICTED: Macaca mulatta similar to transcription factor B2, mitochondrial (LOC710669), mRNA [XR_011737]
CP 1.42E-04 13.285389 down 1.122256 down 1.274657 down Homo sapiens ceruloplasmin (ferroxidase) (CP), mRNA [NM_000096]
TOLLIP 1.59E-04 12.683504 down 1.156986 down 1.00844 down Homo sapiens toll interacting protein (TOLLIP), mRNA [NM_019009]
DARS 3.99E-05 12.632657 down 3.152794 down 1.10567 down Homo sapiens aspartyl-tRNA synthetase (DARS), mRNA [NM_001349]
CKLF 4.24E-04 12.476327 down 1.130294 down 1.064736 down Homo sapiens chemokine-like factor (CKLF), transcript variant 1, mRNA [NM_016951]
STT3B 1.13E-04 12.457355 down 2.027118 down 1.030927 down Homo sapiens STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae) (STT3B), mRNA [NM_178862]
TXNDC11 4.40E-05 12.377014 down 1.525444 down 1.011564 down Homo sapiens thioredoxin domain containing 11 (TXNDC11), mRNA [NM_015914]
CR603105 9.80E-04 12.209639 down 1.284419 down 1.155491 down full-length cDNA clone CS0DF006YN22 of Fetal brain of Homo sapiens (human) [CR603105]
XR_010672 5.09E-05 11.634537 down 1.602301 down 1.059423 up PREDICTED: Macaca mulatta similar to Molybdenum cofactor synthesis protein 2 large subunit (Molybdopterin synthase large subunit) (MPT synthase large subunit) (MOCS2B) (MOCO1-B) (LOC703049), mRNA [XR_010672]
GDE1 0.03917646 11.536806 down 1.190901 up 1.20255 up Homo sapiens membrane interacting protein of RGS16 (MIR16), mRNA [NM_016641]
CFHR2 2.07E-04 11.37657 down 1.208862 down 1.032327 down Homo sapiens complement factor H-related 2 (CFHR2), mRNA [NM_005666]
RPL30 0.03067462 11.374878 down 1.173423 up 1.096937 up Homo sapiens ribosomal protein L30 (RPL30), mRNA [NM_000989]
XM_495885 0.002429009 11.322625 down 1.165255 down 1.156577 down PREDICTED: Homo sapiens similar to ribosomal protein S12 (LOC440055), mRNA [XM_495885]
NDUFB1 2.13E-04 11.293429 down 1.404433 down 1.277028 up Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7 kDa (NDUFB1), mRNA [NM_004545]
NM_032807 2.89E-04 11.240869 down 1.075345 down 1.014724 down Homo sapiens F-box protein, helicase, 18 (FBXO18), transcript variant 1, mRNA. [NM_032807]
CSGALNACT 2 1.34E-05 11.216295 down 1.714551 down 1.080183 down Homo sapiens chondroitin sulfate GalNAcT-2 (GALNACT-2), mRNA [NM_018590]
NM_022333 0.002598488 10.94874 down 1.130622 up 1.014866 down Homo sapiens TIA1 cytotoxic granule-associated RNA binding protein-like 1 (TIAL1), ranscript variant 2, mRNA [NM_022333]
NM_032807 0.001172931 10.342792 down 1.522541 down 1.139832 down Homo sapiens F-box protein, helicase, 18 (FBXO18), transcript variant 1, mRNA. [NM_032807]
AAMP 2.62E-05 10.171815 down 1.560637 down 1.085371 down Homo sapiens angio-associated, migratory cell protein (AAMP), mRNA [NM_001087]
ESF1 1.02E-07 9.745275 down 1.620818 down 1.008674 down Homo sapiens ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) (ESF1), mRNA [NM_016649]
DOCK7 0.01799708 9.74066 down 1.174452 up 1.171709 up Homo sapiens dedicator of cytokinesis 7 (DOCK7), mRNA [NM_033407]
DDX3Y 4.78E-06 9.687978 down 1.356089 down 1.134329 down Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked (DDX3Y), mRNA [NM_004660]
XIAP 3.65E-05 9.587557 down 1.882389 down 1.280735 up Homo sapiens baculoviral IAP repeat-containing 4 (BIRC4), mRNA [NM_001167]
TRPC4AP 9.51E-05 9.4549885 down 1.340843 down 1.07043 up Homo sapiens transient receptor potential cation channel, subfamily C, member 4 associated protein (TRPC4AP), transcript variant 1, mRNA [NM_015638]
ADK 1.63E-04 9.386349 down 5.639505 down 1.368648 down Homo sapiens adenosine kinase (ADK), transcript variant ADK-short, mRNA [NM_001123]
NM_0010022 92 3.92E-04 9.258961 down 1.016391 up 1.220083 down Homo sapiens chromosome 1 open reading frame 139 (C1orf139), transcript variant 2, mRNA. [NM_001002292]