Figure 1

Expression profiles of the isochore for the three tissues on chromosome 10. The Y axis measures the isochores' GC levels (positive values -- light blue line) and their respective expression levels (E _L -- Equation (1)) for the brain, liver, and muscle tissues (negative values -- red, dark blue, and green lines, respectively). High expression corresponds to peaks in the lines. The red and black boxes highlight areas where the high GC level is clearly accompanied by high expression. The black vertical line in the red box marks the location of the 10 Mm62 H3 isochore.