From: Searching ChIP-seq genomic islands for combinatorial regulatory codes in mouse embryonic stem cells
Cofactor expression pattern | ES-up feature | ES-down feature |
---|---|---|
Positive fold change | ES activator (EA) | ES repressor (ER) |
Negative fold change | DF repressor (DR) | DF activator (DA) |
Uniformly high | EA and/or DR | ER and/or DA |