Figure 2

Representative log ₂ AEI distributions: GAB2, GNB1L and DISC1. Each pair of bars represents the gDNA-based (red) and cDNA-based (blue) log₂AEI ratios from a single sample. cDNA-based log₂ AEI ratios are arranged in order from most- negative on the left to most-positive on the right, forming a distinct distribution of log₂AEI ratios for each gene. The selected genes illustrate three common patterns of log₂AEI population distributions: uniphasic, skewed and biphasic. As described in the text and in Additional file 4, log₂AEI distributions often contain useful information concerning the number, location and linkage of the regulatory genetic variants that produce AEI in each gene.