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Table 2 List of genes involved in the regulation of the cytoskeleton and affected by DEHP

From: Transcriptomic effects of di-(2-ethylhexyl)-phthalate in Syrian hamster embryo cells: an important role of early cytoskeleton disturbances in carcinogenesis?

 

5 hrs

24 hrs

Up-regulated genes

coro1C* (25 - 50 μM)

kif23* (25 - 50 μM)

cdh3* (12.5 - 25 - 50 μM)

ctnnbip1* (25 μM)

coro1C* (25 - 50 μM)

kif23* (25 - 50 μM)

col1a1* (50 μM)

crip1* (25 - 50 μM)

calml3* (12.5 - 25 - 50 μM)

dclk1* (25 - 50 μM)

cttnbp2* (50 μM)

plekha5

tubb2b

β-actin

Down-regulated genes

nrp2* (25 - 50 μM)

nrp2* (25 - 50 μM)

thbs* (50 μM)

flrt2* (50 μM)

cdh3* (12.5 - 25 - 50 μM)

has2* (50 μM)

enah* (50 μM)

lrcc8a* (50 μM)

snx6* (50 μM)

ctnnbip1* (12.5 μM)

nid2

thy1

  1. This table summarizes the genes studied using qPCR. (*) indicates significant effects of DEHP (2.0-fold over- or under-expression) at concentration(s) specified in brackets. A trend for up- or down-regulation was found for the other genes (no concentration reported).