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Table 1 Patient demographics for frontal cortex and cerebellar brain samples included in this study.

From: Altered microRNA expression in frontotemporal lobar degeneration with TDP-43 pathology caused by progranulin mutations

Mutation status

N

FTLD-TDP Type 1

FTLD-TDP Type 2

FTLD-TDP Type 3

Male/Female

Mean age at death ± SD

PGRN + Cortex

8

8

n/a

n/a

3/5

75.5 ± 10.1 (63-87)

PGRN -

Cortex

32

12

11

9

18/14

74.9 ± 10.5 (52-97)

PGRN +

Cerebellum

10

10

n/a

n/a

7/3

72.3 ± 10.3 (56-87)

PGRN -

Cerebellum

30

12

12

6

16/14

73.8 ± 10.3 (52-97)

  1. * There was overlap of 6 PGRN+ and 25 PGRN- samples between the cerebellum and frontal cortex analyses. n/a = not applicable
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BMC Genomics

ISSN: 1471-2164

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