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Table 2 Statistics of putative genes involved in camptothecin biosynthesisa

From: Pyrosequencing of the Camptotheca acuminata transcriptome reveals putative genes involved in camptothecin biosynthesis and transport

Enzyme code Name of enzyme Number of unigenes in cDNA library Number of ESTs in cDNA library Number of nucleotides in GenBank
2.3.1.9 acetoacetyl-CoA thiolase 2 15 0
2.3.3.10 HMG-CoA synthase 4 7 1
1.1.1.34 HMG-CoA reductase 2 9 3
2.7.1.36 mevalonate kinase 1 5 0
2.7.4.2 phosphomevalonate kinase 2 2 0
4.1.1.33 mevalonate-5-diphosphate decarboxylase 2 6 0
2.2.1.7 DXP synthase 8 105 0
1.1.1.267 DXP reductoisomerase 1 19 1
2.7.7.60 MEP cytidylyltransferase 0 0 0
2.7.1.148 CDP-ME kinase 3 3 0
4.6.1.12 MECDP synthase 1 1 0
1.17.7.1 4-hydroxy-3-methylbut-2-enyl-diphosphate synthase 1 33 0
1.17.1.2 4-hydroxy-3-methylbut-2-enyl-diphosphate reductase 1 13 0
5.3.3.2 isopentenyl-PP isomerase 2 11 1
2.5.1.10 farnesyl diphosphate synthase 4 13 0
1.14.14.1 geraniol 10-hydroxylase 1 11 0
1.-.-.- 10-HG oxidoreductase 3 84 1
1.3.3.9 secologanin synthase 17 165 0
4.2.1.20 β-subunit of tryptophan synthase 4 4 2
4.1.1.28 tryptophan decarboxylase 1 1 2
4.3.3.2 strictosidine synthase 6 14 0
Total number 66 521 11
  1. Notes: a--Total numbers when annotated against Nr, Swissprot and Kegg databases.