Figure 8
From: Identification of novel targets for breast cancer by exploring gene switches on a genome scale
CREB binding sites on the promoter of TACSTD2. We extracted the promoter sequence of TACSTDs from TRED (the Transcriptional Regulatory Element Database, http://rulai.cshl.edu/TRED), and searched for the CREB binding sites by comparing the promoter sequences with the position weight matrix (PWM). The TRANSFAC http://www.gene-regulation.com and the JASPAR http://jaspar.genereg.net/ databases provide different versions of CREB binding PWM. Nevertheless, there are four potential CREB binding sites that are predicted by both of the PWMs on the promoter of TACSTD2.