Dietary manipulation results in deregulation of a subset of genes shared by both sexes. A: Genes differentially regulated in both with a fold change of ≥ ± 1.5 for either of the comparisons control vs MSG, control vs TFA or TFA vs TFA+MSG. (P < 0.01). B: A selection of X-linked and C: Y-linked cardiac genes analyzed by microarray. Heatmap shows genes represented horizontally and diet groups represented by the vertical rows: red color signals genes with increased expression whilst blue indicated a reduction of expression, with a stringency ≥ ± 1.5-fold change.