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Table 8 Gene Ontology terms enriched among the CNVs

From: Whole genome resequencing of black Angus and Holstein cattle for SNP and CNV discovery

Ontology

GO ID

Description

Animal

P-BA

P-HOL

BP

GO:0032502

Developmental process

Both

4.3E-21

3.5E-40

BP

GO:0032501

Multicellular organismal process

Both

6E-34

3.4E-67

BP

GO:0050789

Regulation of biological process

Both

0.00042

0.00015

BP

GO:0002376

Immune system process

Both

2.4E-19

1.4E-17

BP

GO:0016043

Cellular component organization

Both

1.3E-07

9.7E -12

BP

GO:0065007

Biological regulation

Both

5.5E-05

9.2E-05

BP

GO:0048518

Positive regulation of biological process

Both

1.3E-35

2.6E-29

BP

GO:0048519

Negative regulation of biological process

Both

5.7E-16

1E-30

BP

GO:0022610

Biological adhesion

Both

8.5E-06

0.028

BP

GO:0016265

Death

Both

1.5E-13

2.3E-07

BP

GO:0009987

Cellular process

Both

0.011

0.077

BP

GO:0008152

Metabolic process

Both

0.0051

0.015

BP

GO:0051234

Establishment of localization

Both

0.011

0.00069

BP

GO:0051179

Localization

Both

0.002

3.5E-07

BP

GO:0040007

Growth

Both

9.7E-07

3.8E-16

BP

GO:0050896

Response to stimulus

Both

3.2E-30

9.1E-41

BP

GO:0044085

Cellular component biogenesis

Both

0.00072

0.0044

BP

GO:0040011

Locomotion

BA

5.4E-12

-

BP

GO:0000003

Reproduction

HOL

-

1.6E-25

BP

GO:0022414

Reproductive process

HOL

-

3.8E-18

CC

GO:0032991

Macromolecular complex

Both

0.007

1.6E-05

CC

GO:0005623

Cell

Both

0.0016

0.00025

CC

GO:0044464

Cell part

Both

0.0016

0.00025

CC

GO:0044421

Extracellular region part

Both

1.2E-14

5.8E-13

CC

GO:0005576

Extracellular region

Both

2E-08

7.8E-07

CC

GO:0043226

Organelle

Both

0.0054

4.3E-07

CC

GO:0044422

Organelle part

Both

0.00024

6.8E-10

CC

GO:0031974

Membrane-enclosed lumen

HOL

-

4.5E-06

MF

GO:0060089

Molecular transducer activity

Both

0.013

0.0031

MF

GO:0005215

Transporter activity

Both

0.07

0.43

MF

GO:0003824

Catalytic activity

Both

0.071

0.095

MF

GO:0005488

Binding

Both

0.0015

0.0032

MF

GO:0030528

Transcription regulator activity

HOL

-

0.16

MF

GO:0030234

Enzyme regulator activity

HOL

-

3.6E-09

  1. GO IDs from the three GO ontologies (BP = Biological Process; CC = Cellular Component; MF = Molecular Function) enriched among the CNV gains in Black Angus (BA), Holstein (HOL), or both animals (Both). P-values are provided, when applicable, for the subset of CNVs detected as gains in the Black Angus animal (P-BA) and the subset detected as gains in the Holstein animal (P-HOL).