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Figure 3 | BMC Genomics

Figure 3

From: Effects of genome-wide copy number variation on expression in mammalian cells

Figure 3

Cis and trans ceQTLs. Every point represents the regulation of a gene (y-axis) by a marker (x-axis). White streaks are centromeric regions. Horizontal marginal shows number of genes regulated in trans by each loci. The probability that a marker would regulate more than 4 genes is 0.31 (FDR < 0.4, light blue line) and more than 7 genes is 0.008 (FDR < 0.01, red line). Vertical marginal illustrates number of trans ceQTLs regulating each gene. The likelihood that a gene is regulated by more than 16 trans ceQTLs is 0.29 (FDR < 0.3, light blue line) and more than 23 is 0.01 (FDR < 0.01, red line). Both highly regulatory loci and highly regulated genes are evident.

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