Maxicircle-encoded Sylvio X10 gRNA for MURF2 RNA editing. Alignment of the MURF2 gRNA from Sylvio X10 maxicircle aligned with the predicted editing pattern for the 5' end of the MURF2 transcript. Standard Watson-Crick base pairing is shown by '|' and G-U wobble base pairing is represented by ':'. The cognate CL Brener maxicircle-encoded gRNA is shown below. The transitions between the two gRNAs are underlined in CL Brener.