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Table 1 Genes in the Sylvio X10, CL Brener and Esmeraldo maxicircle consensus sequences

From: The Trypanosoma cruzi Sylvio X10 strain maxicircle sequence: the third musketeer

   

position (5'-3')

  

length

 

Gene

Editing

Sylvio

CL Brener

Esmeraldo

Sylvio

CL Brener

Esmeraldo

     

CLADE A

CLADE B

CLADE C

12S rRNA

-

1-1159

1-1161

1-1160

1159

1161

1160

9S rRNA

-

1203-1812

1200-1808

1197-1804

610

608

607

ND8

extensive

1856-2135

1853-2131

1957-2127

280

279

271

ND9

extensive

2198-2547

2195-2532

2192-2545

350

338

354

MURF5

none

2541-2801

2526-2789

2522-2788

261

264

267

ND7

extensive

2877-3623

2857-3611

2862-3617

747

755

756

COIII

extensive

3697-4116

3678-4100

2685-4109

420

424

425

Cyb

5' end

4189-5269

4175-5254

4167-5246

1081

1080

1080

ATPase 6

extensive

5310-5639

5292-5627

5288-5622

330

336

335

MURF1

none

5696-7036

5675-7015

5681-7029

1341

1340

1347

CR3*

extensive

7023-7144

7002-7120

7016-7136

~122

~119

~121

NDI

none

7138-8079

7116-8057

7132-8073

942

942

942

COII+gRNA

internal

8093-8737

8071-8715

8088-8733

645

645

646

MURF2

5' end

8748-9800

8725-9780

8750-9794

1053

1056

1045

COI

none

9791-11440

9771-11420

9785-11434

1650

1650

1650

CR4

extensive

11492-11700

11471-11677

11487-11658

209

207

172

MURF2 gRNA

-

11764-11804

11744-11784

-

41

41

-

ND4

none

11802-13114

11782-13095

11659-12872

1313

1314

1214

ND3

extensive

13108-13300

13087-13279

12864-13051

193

193

188

RPS12

extensive

13377-13564

13357-13547

13129-13315

188

191

187

ND5

none

13586-15185**

13568-15337

13335-15105

1600+

1770

1771

  1. Gene positions are given relative to the start of the 12S rRNA
  2. *CR3 5' and 3' end positions are uncertain
  3. **partial sequence