Conserved metazoan signal transduction pathway components identified in the P. hawaiensis transcriptome. These results were generated by using BLAST to compare sequences from known homologues against the full Newbler v2.5 assembly (see Additional File 9 and text for details), with genes identified marked in red. Genes outlined in grey with grey typeface indicate genes without D. melanogaster homologues. Pathway schematics modified from KEGG pathway model images http://www.genome.jp/kegg/kegg1.html. (A) Notch pathway. (B) TGFβ pathway. (C) Wnt pathway. (D) Hedgehog pathway. (E) Janus Kinase (JAK)-signal transducer and activator of transcription (STAT) pathway. (F) Mitogen-activated protein Kinase (MAPK) pathway.