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Table 2 GRAFS-based comparison of GPCR repertoires

From: The repertoire of G protein-coupled receptors in the human parasite Schistosoma mansoni and the model organism Schmidtea mediterranea

   H. sapiens A. gambiae D. melanogaster C. elegans S. mansoni S.mediterranea
R AMIN (α) 44 18 21 20 24 66
  MEC (α) 22 2 1 1 0 0
  MTN (α) 3 2 2 0 0 9
  OPN (α) 11 12 8 1 4 7
  PTGER (α) 13 0 0 0 0 0
  PEP (β) 43 29 21 31 36 130
  CHEM (γ) 43 0 0 0 0 0
  MCHR (γ) 1 0 0 0 0 0
  SOG (γ) 10 3 5 10 0 0
  LGR (δ) 7 3 4 1 0 0
  MRG (δ) 7 0 0 0 0 0
  OLF (δ) 494 0 0 0 0 0
  PUR (δ) 35 0 0 0 0 0
  PROF1 0 0 0 0 19 47
  Unclassified 20 77 79 124 22 159
F FZD/SMO 11 13 5 5 5 11
  TAS2 13 0 0 0 0 0
G GLR 24 8 9 6 2 9
A/S ADH 27 13 5 5 3 9
  SEC 20 1 13 5 2 1
  PARF1 0 0 0 0 0 12
  1. The GPCR repertoires of S. mansoni and S. mediterranea are shown from a GRAFS-based perspective, alongside those of other organisms with characterized GPCR complements. For Rhodopsin sub-classification, BLAST searches were used to help tentatively assign putative ligands to receptors omitted from phylogenetic analysis.