Figure 4

Comparison of methylation levels between LHC-BS and BS-PCR. The top of the figure represents the methylation levels of CpGs in the YH blood and mDC samples that were detected by LHC-BS. The height of the red box represents the methylation level of a CpG site. Each rectangle underneath represents the methylation status of a CG in a fragment that was detected by BS-PCR. Red represents a methylated CpG site, and green represents a nonmethylated CpG site. The P values were calculated using the chi-square or Fisher's tests. (a) Comparison of the methylation levels that were detected in a moderately methylated region of the 5'UTR of the MOBP gene, (b) a mildly methylated region of the DSPP gene and two highly methylated regions of the WDR37 (c) and DIP2B (d) genes using either HLC-BS or BS-PCR.