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Table 7 The top 30 Ae. aegypti genes with highest piRNA density

From: The mosquito Aedes aegypti has a large genome size and high transposable element load but contains a low proportion of transposon-specific piRNAs

Gene

Gene length (bps.)

Unique mapping piRNAs1

piRNA density (piRNAs/gene bps.)

strand percent +/-

gene inside piRNA cluster

Function of best match (if available) and species

Best match database

Best match accession

AAEL011224

303

16488

54.6

100/0

yes

hypothetical protein

VectorBase

AAEL011224

AAEL007866

1334

10651

8.0

99/1

yes

putative NS1 protein, Aedes flavivirus

NR

YP_003084126

AAEL007861

1182

4356

3.7

100/0

yes

uncharacterized transmembrane protein DDB_G0289901, Dictyostelium discoideum

Swiss-Prot

Y8625_DICDI

AAEL010454

1425

4084

2.9

90/10

yes

hypothetical protein

VectorBase

AAEL010454

AAEL000120

1020

1432

1.4

94/6

no

nucleoprotein N, bovine ephemeral fever virus

Swiss-Prot

NCAP_BEFV

AAEL009005

629

856

1.4

100/0

no

adult cuticle protein, Aedes aegypti

VectorBase

AAEL009005

AAEL005277

4038

4891

1.2

100/0

yes

Zinc finger protein on ecdysone puffs, Drosophila melanogaster

Swiss-Prot

PEP_DROME

AAEL009525

1236

1494

1.2

100/0

no

nucleoprotein putative, Aedes aegypti

VectorBase

AAEL009525

AAEL005213

1377

1582

1.1

100/0

no

hypothetical protein

VectorBase

AAEL005213

AAEL000668

1333

1522

1.1

100/0

no

conserved hypothetical protein

VectorBase

AAEL000668

AAEL001004

6251

7009

1.1

100/0

no

protein maelstrom homolog, Aedes aegypti

Swiss-Prot

MAEL_AEDAE

AAEL007686

2253

2439

1.1

100/0

no

Transcription factor MafB, Coturnix coturnix jopnica

Swiss-Prot

MAFB_COTJA

AAEL001772

2562

2643

1.0

100/0

no

RNA-dependent RNA polymerase, Nyamanini virus

NR

YP_002905337

AAEL005456

966

841

0.9

100/0

yes

nucleoprotein putative, Aedes aegypti

VectorBase

AAEL005456

AAEL000808

978

811

0.8

100/0

yes

nucleoprotein putative, Aedes aegypti

VectorBase

AAEL000808

AAEL013013

1088

862

0.8

100/0

no

hypothetical protein

VectorBase

AAEL013013

AAEL006843

21911

17268

0.8

100/0

no

NEDD4-binding protein 2, Homo sapiens

Swiss-Prot

N4BP2_HUMAN

AAEL006159

330

247

0.8

100/0

yes

Peritrophin-1, Anopheles gambiae

Swiss-Prot

PE1_ANOGA

AAEL005225

762

570

0.7

100/0

no

conserved hypothetical protein

VectorBase

AAEL005225

AAEL004959

1242

914

0.7

100/0

no

nucleoprotein putative, Aedes aegypti

VectorBase

AAEL004959

AAEL009873

1602

1142

0.7

78/22

no

nucleoprotein, bovine ephemeral fever virus

Swiss-Prot

NCAP_BEFV

AAEL005768

738

511

0.7

100/0

no

hypothetical protein

VectorBase

AAEL005768

AAEL007499

579

372

0.6

100/0

no

hypothetical protein

VectorBase

AAEL007499

AAEL007844

2572

1490

0.6

100/0

no

glycoprotein, spring viremia of carp virus

NR

ABB13496

AAEL010887

60098

34174

0.6

100/0

no

Myosin heavy chain IB, Acanthamoeba castellanii

Swiss-Prot

MYSB_ACACA

AAEL000673

1461

753

0.5

100/0

no

arbohydrate kinase domain-containing protein, Mus musculus

Swiss-Prot

CARKD_MOUSE

AAEL000276

71446

36638

0.5

1/99

no

VPRBP protein, Culex quinquefasciatus

NR

XP_001865214

AAEL012346

1177

598

0.5

100/0

no

hypothetical protein

VectorBase

AAEL012346

AAEL006704

1356

684

0.5

100/0

no

fibrinogen and fibronectin, Aedes aegypti

VectorBase

AAEL006704

AAEL003715

615

298

0.5

100/0

no

hypothetical protein

VectorBase

AAEL003715