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Table 1 QTLs from classical phenotypes overlapping with eQTLs

From: Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease

Chromosome Mb Record Phenotype Max LRS Max LRS Location (Chr: Mb)
3 20-30 12958 Blood chemistry, cardiovascular system: White blood cell count of 14-week old males 19 Chr3: 28.293133
4 28-35 10410 Immune function: Antigenic activity of irradiated BXD spleen cells for Thy1+CD3+CD4+CD8- T-cell clone TGVH32 31 Chr4: 31.651725
17 25-45 11025 Infectious disease, immune function: Chlamydia psittaci (6BC) infection response (10^4 IFU ip), pathogen load in peritoneal cavity at 30 days among surviving 3-5 month males 33.6 Chr17: 31.769795
17 25-45 10466 Immune function, gastrointestinal system: Intestinal intraepithelial gamma-delta type T lymphocytes (i-IELs) in 2-6 month old adults based on receptor expression (V-gamma-7 positive, Vgamma-4 negative T cells) 33.1 Chr17: 32.068297
17 25-45 10236 Proliferation of JTL-G12 cells (T cell clone) with 50 ug/ml GAT (Glu60, Ala30, Tyr10) 24.5 Chr17: 32.068297
17 25-45 10238 Proliferation of JTL-G12.8 (Tcell clone) with 50 ug/ml GAT (Glu60, Ala30, Tyr10) 26.7 Chr17: 32.068297
17 25-45 10441 Anti-F antigen (liver protein) titer, experiment 1 19.1 Chr17: 26.950946
17 25-45 12672 Infectious disease, immune function: Ectromelia virus survival over two weeks after a 90 pfu intranasal inoculation, males and females between 40 and 150 days of age, residuals corrected for sex, age, and body weight 19.5 Chr17: 31.179359