Skip to main content

Table 2 Enriched functional categories of genes correlating with specific extracellular protein production rate

From: Correlation of gene expression and protein production rate - a system wide study

ID

Description

Expression

% of ex-pressed

% of annotated

p-value

Intepretation

IPR000639

Epoxide hydrolase-like

C07wN

2.2

26.7

0.000

Various

IPR006163

Phosphopantetheine-binding

C07wN

2.7

18.5

0.000

2ndary metabolism?

IPR000873

AMP-dependent synthetase/ligase

C07wN

2.7

12.8

0.001

2ndary metabolism?

IPR001579

Glycoside hydrolase, chitinase active site

C07wN

1.6

27.3

0.001

Secreted

IPR002938

Monooxygenase, FAD-binding

C07wN

1.6

23.1

0.002

2ndary metabolism?

IPR000209

Peptidase S8/S53, subtilisin/kexin/sedolisin

C07wN

2.2

14.8

0.003

Protein degradation

IPR001223

Glycoside hydrolase, family 18, catalytic domain

C07wN

1.6

18.8

0.005

Secreted

IPR000073

Alpha/beta hydrolase fold-1

C07wN

2.2

10.3

0.010

2ndary metabolism?

IPR011701

Major facilitator superfamily MFS-1

C07wN

4.4

5.3

0.017

Transporter

IPR003663

Sugar/inositol transporter

C07wN

2.2

8.3

0.020

Transporter

IPR000217

Tubulin

-C07wN

1.6

60.0

0.000

Cytoskeleton

IPR001353

Proteasome, subunit alpha/beta

-C07wN

2.2

28.6

0.000

Protein degradation

IPR000504

RNA recognition motif, RNP-1

-C07wN

2.7

8.8

0.008

Protein synthesis

IPR000719

Protein kinase, catalytic domain

-C07wN

3.8

5.8

0.016

Regulation

12.04

translation

-C07wN

3.6

14.0

0.017

Protein synthesis

12.04.01

translation initiation

-C07wN

2.3

18.5

0.018

Protein synthesis

IPR000623

Shikimate kinase

C08

0.7

60.0

0.001

Various

IPR011701

Major facilitator superfamily MFS-1

C08

3.9

10.5

0.003

Transporter

IPR003819

Taurine catabolism dioxygenase TauD/TfdA

C08

0.7

42.9

0.003

Sulphur metabolism

IPR006094

FAD linked oxidase, N-terminal

C08

1.2

19.2

0.007

2ndary metabolism?

IPR003663

Sugar/inositol transporter

C08

1.7

14.6

0.008

Transporter

IPR006163

Phosphopantetheine-binding

C08

1.2

18.5

0.009

2ndary metabolism?

IPR002403

Cytochrome P450, E-class, group IV

C08

1.0

22.2

0.010

2ndary metabolism?

IPR004841

Amino acid permease domain

C08

1.2

15.6

0.018

Transporter

IPR000254

Cellulose-binding domain, fungal

C08

0.7

23.1

0.023

Secreted

IPR002018

Carboxylesterase, type B

C08

0.7

21.4

0.028

Secreted

IPR002085

Alcohol dehydrogenase superfamily, zinc-containing

C08

1.5

11.8

0.036

2ndary metabolism?

IPR001452

Src homology-3 domain

-C08

1.6

28.0

0.000

Cytoskeleton

IPR001353

Proteasome, subunit alpha/beta

-C08

1.1

35.7

0.001

Protein degradation

IPR002423

Chaperonin Cpn60/TCP-1

-C08

0.9

40.0

0.001

Cytoskeleton

IPR002108

Actin-binding, cofilin/tropomyosin type

-C08

0.7

60.0

0.001

Cytoskeleton

IPR005937

26S proteasome subunit P45

-C08

0.7

50.0

0.003

Protein degradation

IPR000717

Proteasome component (PCI) domain

-C08

0.9

30.8

0.004

Protein degradation

IPR004827

Basic-leucine zipper (bZIP) transcription factor

-C08

1.1

22.7

0.005

Regulation

IPR000594

UBA/THIF-type NAD/FAD binding fold

-C08

0.7

37.5

0.007

Protein degradation

12.04

translation

-C08

2.9

24.6

0.012

Protein synthesis

12.04.01

translation initiation

-C08

1.6

29.6

0.017

Protein synthesis

IPR001199

Cytochrome b5

-C08

0.9

19.0

0.024

Energy

IPR003593

ATPase, AAA+ type, core

-C08

2.2

9.8

0.046

Various

  1. 'ID' is InterPro or Funcat identifier. 'Description' is short name for the category. 'Expression' is type of expression behaviour the genes have. 'C07wN' genes belong to a pair of adjacent genes that both have correlation to specific protein production rate (SPPR) above 0.7, '-C07wN' is the opposite case, 'C08' genes have correlation to SPPR above 0.8 and '-C08' is again the opposite. '% of expressed' is the percentage of genes among the group of genes with same expression that belong to the annotation category. '% of annotated' is the percentage of genes among all genes that belong to the annotation category. 'p-value' is for the significance of enrichment. 'Intepretation' is a biological consept to which the genes relate to as intepreted by the authors.