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Table 1 Basic information on PCSK genes and whole genome expression correlations

From: Identification of proprotein convertase substrates using genome-wide expression correlation analysis

     Top 5% (n = 861/867) Bottom 5% (n = 861/867)  
gene id # correlating genes in GeneSapiens (5%) # of common samples with other genes # genes with furin/general PC cleavage site and signal peptide max/min correlation # genes with furin/general PC cleavage site and signal peptide max/min correlation p value*
PCSK1 ensg00000175426 17330 (867) 445-1698 160 0.810/0.450 102 -0.246/-0.479 1.24E-4
PCSK2 ensg00000125851 17330 (867) 445-1698 170 0.871/0.541 96 -0.334/-0.637 5.10E-7
FURIN ensg00000140564 17330 (867) 445-1698 161 0.652/0.332 83 -0.253/-0.512 4.21E-9/2.10E-7
PCSK4 ensg00000115257 17215 (861) 497-668 104 0.592/0.300 67 -0.236/-0.480 2.25E-4
PCSK5 ensg00000099139 17330 (867) 445-1698 116 0.636/0.232 158 -0.245/-0.493 4.45E-3
PCSK6 ensg00000140479 17330 (867) 445-1698 165 0.833/0.302 60 -0.277/-0.526 < 1E-10
PCSK7 ensg00000160613 17330 (867) 445-1698 111 0.571/0.312 109 -0.236/-0.481 0.71
  1. Genes with PCSK cleavage site and signal peptide accumulate in top 5% correlating genes
  2. * Chi-square test for top 5% vs bottom 5% correlating genes/fraction of genes with PCSK detection site and signal peptide from all 5% genes.