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Table 2 Microarray and RT-qPCR results for known TH-regulated genes.

From: Thyroid hormone-regulated gene expression in juvenile mouse liver: identification of thyroid response elements using microarray profiling and in silico analyses

  

Microarray

RT-qPCR

Gene

Group

FC

p-value

FC

p-value

Male Pups

    

Thrsp

Hypo

-2.8

0.036

-5.0

0.032

 

Hyper

1.6

0.999

2.4

0.170

Dio1

Hypo

-2.6

0.000

-4.9

0.015

 

Hyper

1.3

0.999

1.5

0.029

Me1

Hypo

-1.4

0.379

-1.4

0.099

 

Hyper

1.3

0.632

1.5

0.017

Female Pups

    

Thrsp

Hypo

-2.7

0.000

-5.0

0.033

 

Hyper

2.4

0.019

4.6

0.010

Dio1

Hypo

-3.2

0.000

-7.8

0.001

 

Hyper

1.2

0.983

1.5

0.008

Me1

Hypo

-1.4

0.045

-1.3

0.143

 

Hyper

1.3

0.095

1.7

0.002

  1. Fold-changes are presented for treated animals relative to control animals; n = 4 for all groups except for hyper, where n = 5. Fold-changes (FC) and p-values are in bold when p ≤ 0.05.
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BMC Genomics

ISSN: 1471-2164

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