Patterns of genetic differentiation and linkage mapping results for chromosomes with large QTL . Patterns of the moving average of allele frequency differences between Holstein and Charolais cattle (MA_δ, represented by diamonds) and the maximum F-ratio of the linkage mapping study with Holstein and Charolais founders (Fmax, represented by the curve) across BTA5, 6 and 18. The horizontal lines show the average values of MA_δ for each chromosome. For BTA5, the black triangle on the x-axis indicates the position of the SILV gene. For BTA18, the black triangle indicates the position of the MC1R gene.