TY - JOUR AU - Davie, Jeremiah J. AU - Earl, Josh AU - de Vries, Stefan PW AU - Ahmed, Azad AU - Hu, Fen Z. AU - Bootsma, Hester J. AU - Stol, Kim AU - Hermans, Peter WM AU - Wadowsky, Robert M. AU - Ehrlich, Garth D. AU - Hays, John P. AU - Campagnari, Anthony A. PY - 2011 DA - 2011/01/26 TI - Comparative analysis and supragenome modeling of twelve Moraxella catarrhalis clinical isolates JO - BMC Genomics SP - 70 VL - 12 IS - 1 AB - M. catarrhalis is a gram-negative, gamma-proteobacterium and an opportunistic human pathogen associated with otitis media (OM) and exacerbations of chronic obstructive pulmonary disease (COPD). With direct and indirect costs for treating these conditions annually exceeding $33 billion in the United States alone, and nearly ubiquitous resistance to beta-lactam antibiotics among M. catarrhalis clinical isolates, a greater understanding of this pathogen's genome and its variability among isolates is needed. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-12-70 DO - 10.1186/1471-2164-12-70 ID - Davie2011 ER -