TY - JOUR AU - Lehne, Benjamin AU - Lewis, Cathryn M. AU - Schlitt, Thomas PY - 2011 DA - 2011/02/01 TI - Exome localization of complex disease association signals JO - BMC Genomics SP - 92 VL - 12 IS - 1 AB - Genome-wide association studies (GWAS) of common diseases have had a tremendous impact on genetic research over the last five years; the field is now moving from microarray-based technology towards next-generation sequencing. To evaluate the potential of association studies for complex diseases based on exome sequencing we analysed the distribution of association signal with respect to protein-coding genes based on GWAS data for seven diseases from the Wellcome Trust Case Control Consortium. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-12-92 DO - 10.1186/1471-2164-12-92 ID - Lehne2011 ER -