Table 3 Number of SNPs per window in the observed and permuted datasets (Crohn's Disease)
From: Exome localization of complex disease association signals
CD | Â | Â | observed | 95% confidence interval | ||||
|---|---|---|---|---|---|---|---|---|
| Â | Distance | total | p < 0.1 | p < 0.01 | p < 0.001 | p < 0.1 | p < 0.01 | p < 0.001 |
| Â | -100 | 2,883 | 277 | 31 | 2 | 246 - 333 | 16 - 44 | 0 - 8 |
| Â | -90 | 3,092 | 286 | 30 | 11 | 266 - 355 | 18 - 46 | 0 - 8 |
| Â | -80 | 3,402 | 351 | 28 | 5 | 294 - 387 | 20 - 50 | 0 - 9 |
| Â | -70 | 3,966 | 396 | 51 | 7 | 347 - 447 | 25 - 56 | 0 - 10 |
| Â | -60 | 4,664 | 450 | 42 | 11 | 412 - 521 | 30 - 65 | 0 - 11 |
Upstream | -50 | 5,324 | 569 | 49 | 6 | 475 - 591 | 36 - 73 | 1 - 12 |
| Â | -40 | 6,444 | 645 | 62 | 9 | 581 - 709 | 45 - 86 | 1 - 14 |
| Â | -30 | 7,651 | 823 | 92 | 22 | 696 - 834 | 55 - 100 | 2 - 15 |
| Â | -20 | 10,451 | 1,099 | 131 | 28 | 963 - 1,127 | 79 - 132 | 4 - 19 |
| Â | -10 | 14,095 | 1,452 | 164 | 31 | 1,311 - 1,508 | 110 - 173 | 6 - 25 |
Gene | 0 | 152,344 | 15,511 | 1,649 | 284 | 14,698 - 15,747 | 1,353 - 1,687 | 109 - 201 |
Exon | 0 | 2,876 | 328 | 40 | 12 | 253 - 323 | 18 - 41 | 0 - 7 |
| Â | 10 | 15,064 | 1,550 | 208 | 38 | 1,403 - 1,609 | 119 - 184 | 6 - 26 |
| Â | 20 | 8,954 | 893 | 110 | 29 | 818 - 973 | 66 - 115 | 3 - 18 |
| Â | 30 | 6,860 | 668 | 75 | 18 | 620 - 752 | 48 - 91 | 1 - 14 |
| Â | 40 | 5,555 | 588 | 70 | 11 | 496 - 617 | 37 - 76 | 1 - 12 |
Downstream | 50 | 4,612 | 444 | 36 | 5 | 408 - 516 | 30 - 64 | 0 - 11 |
| Â | 60 | 4,088 | 413 | 38 | 4 | 358 - 461 | 26 - 58 | 0 -10 |
| Â | 70 | 3,507 | 339 | 32 | 1 | 304 - 399 | 21 - 51 | 0 - 9 |
| Â | 80 | 3,262 | 330 | 35 | 8 | 281 - 373 | 19 - 48 | 0 - 9 |
| Â | 90 | 2,882 | 300 | 30 | 7 | 246 - 332 | 16 - 44 | 0 - 8 |
| Â | 100 | 2,601 | 264 | 46 | 10 | 220 - 301 | 14 - 40 | 0 - 8 |
Total | Â | 274,577 | 27,976 | 3,049 | 559 | 25,443 - 28,892 | 2,183 - 3,283 | 134 - 457 |