Table 2 EA 2018 gene variations associated with key phenotypes
Gene locus in EA 2018 | Gene locus in ATCC 824 | Gene variation sites in EA 2018 | Gene variation sites in ATCC 824 | Protein variation sites in EA 2018 | Protein variation sites in ATCC 824 | Product name |
|---|---|---|---|---|---|---|
Solvent formation related genes | ||||||
CEA_G1048 | CAC1036 | 899(T) | 899(C) | 300(V) | 300(A) | Pyruvate kinase |
CEA_G1755 | CAC1742 | 391(A) | 391(G) | 131(N) | 131(D) | phosphotransacetylase |
CEA_G2463 | CAC2449 | 256(A) | 256(G) | 86(S) | 86(G) | Predicted flavoprotein |
CEA_G2485 | CAC2471 | 439(A) | 438-439(-) | 147-150(R,L,P,I) | 147-150 (G,C,L,Stop codon) | Transcriptional regulator, TetR/AcrR family |
CEA_G2556 | CAC2543 | 241-249 (G,T,A,G, A,T,C,A,T) | 240-241(---) | 81-83(V,D,H) | 80-81(---) | Electron-transferring flavoprotein large subunit |
CEA_G2806 | CAC2798 | 286(A) | 286(G) | 96(M) | 96(V) | NADH:flavin oxidoreductase |
CEA_P0058 | CA_P0059 | 754(A) | 754(C) | 252(N) | 252(H) | Alcohol dehydrogenase |
CEA_P0077 | CA_P0078 | 91(A) | 91(G) | 31(T) | 31(A) | acetyl-CoA acetyltransferase |
CEA_P0140 | CA_P0141 | 566(T) | 566(C) | 189(I) | 189(T) | Periplasmic hydrogenase small subunit, dehydrogenase |
Substrate utilization related genes | ||||||
CEA_G0239 | CAC0234 | 1072(T) | 1072(C) | 358(Stop codon) | 358(Q) | PTS system, fructoso-specific IIBC component |
CEA_G1333 | CAC1319 | 5(T) | 5(C) | 2(I) | 2(T) | Glycerol uptake facilitator protein, GLPF |
CEA_G1472 | CAC1456 | 974(T) | 974(A) | 325(M) | 325(K) | Sugar-binding periplasmic protein |
CEA_G2622 | CAC2613 | 270(T) | 270(G) | 90(C) | 90(W) | Transcriptional regulators of NagC/XylR family |
CEA_G2919 | CAC2912 | 97(A) | 97(C) | 33(T) | 33(P) | Sugar-binding periplasmic protein |
CEA_P0052 | CA_P0053 | 317(C) | 317(T) | 106(P) | 106(L) | Xylanase, glycosyl hydrolase family 10 |
Sporulation related genes | ||||||
CEA_G0080 | CAC0080 | 1160(A) | 1159-1160(-) | 387-392(N,I,Q,D,L,Stop codon) | 387-391(I,Y,K,I,Y,K) | Histidine kinase-like ATPase |
CEA_G0656 | CAC0644 | 1226(T) | 1226(G) | 409(V) | 409(G) | Spore germination protein gerKA |
CEA_G0710 | CAC0699 | 416(C) | 416(T) | 139(T) | 139(I) | Spore photoproduct lyase, splB |
CEA_G2066 | CAC2052 | 688(A) | 687-688(-) | 230-248 (18 amino acid) | 230-238 (7 amino acid and a Stop Codon) | DNA-dependent RNA polymerase sigma subunit |
CEA_G3736 | CAC3729 | 374(T) | 374(C) | 125(L) | 125(P) | Stage 0 sporulation J, ParB family of DNA-binding proteins |
CEA_P0016 | CA_P0017 | 11,245(G,A) | 11,245(T,C) | 4,82(E,G) | 4,82(A,V) | Spore germination protein, GRKB |
CEA_P0019 | CA_P0020 | 1120(C) | 1120(T) | 407(A) | 407(V) | Spore germination protein, GRKA |
CEA_P0021 | CA_P0022 | -151(T) | 104(C) | 1(---) | 1-85(85 amino acids insertion) | Spore germination protein, GRKB |