Table 4 Differences (p-value) in diabetes related traits in the 8 confirmed bimodal genes for those in the high compared with those in the low RNA expression mode.
From: Bimodal distribution of RNA expression levels in human skeletal muscle tissue
Gene | Δ BMIa | Δ %fata | Δ log10(Mlow)b | Δ AIRc |
|---|---|---|---|---|
GSTM1 | -0.408 (p = 0.67) | -0.88 (p = 0.28) | 0.015 (p = 0.46) | -1.73 (p = 0.96) |
HLA-DRB1 | 2.04 (p = 0.09) | 1.15 (p = 0.32) | -0.0033 (p = 0.89) | 31.6 (p = 0.49) |
ERAP2 | -0.122 (p = 0.9) | 0.472 (p = 0.58) | -0.0033 (p = 0.86) | 54.4 (p = 0.11) |
HLA-DRB5 | 2.19 (p = 0.072) | 1.22 (p = 0.29) | -0.0095 (p = 0.69) | 31.6 (p = 0.49) |
MAOA | 0.949 (p = 0.29) | 1.78 (p = 0.018) | -0.0001 (p = 1.0) | -44.1 (p = 0.17) |
ACTN3 | 0.71 (p = 0.46) | 0.284 (p = 0.72) | -0.050 (p = 0.0076) | 53.5 (p = 0.14) |
NR4A2 | -0.576 (p = 0.57) | -0.836 (p = 0.36) | -0.010 (p = 0.63) | -2.05 (p = 0.96) |
THNSL2 | 0.695 (p = 0.47) | 0.671 (p = 0.48) | 0.0062 (p = 0.81) | 2.23 (p = 0.97) |