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Table 1 Network characteristics of hub proteins in 3 categories.

From: Assessing the utility of gene co-expression stability in combination with correlation in the analysis of protein-protein interaction networks

Type Average clustering coefficient Average betweenness centrality (10-4)
Category 1 (41 hubs) 0.231 ±0.017* 5.56 ±0.53
Category 2 (264 hubs) 0.099 ±0.016 36.32 ±2.41
Category 3 (315 hubs) 0.154 ±0.004 10.91 ±2.79
  1. Average clustering coefficient and betweenness centrality for 3 categories of hubs based on co-expression correlation and stability. Category 1 – correlation > 0.5, stability > 0.5; Category 2 – correlation <= 0.5, stability > 0.5; Category 3 – correlation <= 0.5, stability <= 0.5. Differences in the distributions of Hub categories 1, 2 and 2, 3 are statistically significant at p << 0.001.
  2. * 95% confidence intervals for average clustering coefficient and betweenness centrality for hubs in each category.