Table 3 Results of predicted interologs from STRING experimental PPIs

Identify homology and transfer

PIDE >30

HVAL >20

Orthologues

Coverage >0.2

E-VALUE <1*e-6

Identified by Inparanoid (default parameters)

E-VALUE< 1*e-10

Benchmark

M.tuberculosis H37Rv high-throughput B2H PPIs dataset

Jaccard coefficient

0.00354

0.00187

0.00289

Precision

0.00375

0.00196

0.00339

Recall

0.0588

0.0384

0.0190

Overlapping PPIs

5

4

5

Benchmark

M. tuberculosis H37Rv predicted functional associations dataset from STRING database(with PPIs score above 770)

Jaccard coefficient

0.285

0.179

0.129

Precision

0.355

0.236

0.239

Recall

0.625

0.422

0.219

Overlapping PPIs

656

830

525