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Table 3 Results of predicted interologs from STRING experimental PPIs

From: Comparative analysis and assessment of M. tuberculosis H37Rv protein-protein interaction datasets

Source PPIs for homology transfer STRING database experimental PPIs
Identify homology and transfer PIDE >30 HVAL >20 Orthologues
  Coverage >0.2 E-VALUE <1*e-6 Identified by Inparanoid (default parameters)
  E-VALUE< 1*e-10   
Benchmark M.tuberculosis H37Rv high-throughput B2H PPIs dataset
Jaccard coefficient 0.00354 0.00187 0.00289
Precision 0.00375 0.00196 0.00339
Recall 0.0588 0.0384 0.0190
Overlapping PPIs 5 4 5
Benchmark M. tuberculosis H37Rv predicted functional associations dataset from STRING database(with PPIs score above 770)
Jaccard coefficient 0.285 0.179 0.129
Precision 0.355 0.236 0.239
Recall 0.625 0.422 0.219
Overlapping PPIs 656 830 525
  1. Predicted interologs from STRING experimental PPIs and a summary of Jaccard coefficient, precision and recall between the interologs datasets and two benchmarks.