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Table 4 Results of predicted interologs from STRING experimental PPIs (with other STRING database prediction support)

From: Comparative analysis and assessment of M. tuberculosis H37Rv protein-protein interaction datasets

Source PPIs for homology transfer STRING database experimental PPIs (with other prediction support)
Identify homology and transfer PIDE >30 HVAL >20 Orthologues
  Coverage >0.2 E-value <1*e-6 Identified by inparanoid (default parameters)
  E-value< 1*e-10   
Benchmark M. tuberculosis H37Rv high-throughput B2H PPIs dataset
Jaccard coefficient 0.00485 0.00225 0.00359
Precision 0.00507 0.00267 0.00401
Recall 0.100 0.0563 0.0331
Overlapping PPIs 5 4 4
Benchmark M. tuberculosis H37Rv predicted functional associations datasetfrom STRING database (with PPIs score above 770)
Jaccard coefficient 0.365 0.233 0.186
Precision 0.467 0.314 0.365
Recall 0.625 0.473 0.275
Overlapping PPIs 651 828 524
  1. Predicted interologs from STRING experimental PPIs (with other STRING database prediction support) and a summary of Jaccard coefficient, precision and recall between the interologs datasets and two benchmarks.