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Table 4 Ranking of subnetworks based on their best new interactions and number of dimensions. The interaction level of known interactions was determined by the arithmetic average of all similarities returned by the vector space model.

From: Can the vector space model be used to identify biological entity activities?

Subnetwork Dimensional Space New Interaction Level of Interaction
6 gene
target
androgen receptor
adrenaline
0.9757
2 disease
gene
HIV
transforming growth factor, beta 1
0.9738
5 drug
target
verapamil
cyclooxygenase 2
0.9597
1 disease
drug
erectile dysfunction
divalproex
0.9470
3 disease
target
arrhythmia
cyclic-gmp phosphodiesterase
0.9272
4 drug
gene
ciclosporin
androgen receptor
0.8211
8 disease
drug
target
alzheimer dementia
acetylsalicylic acid
adrenaline
0.8807
10 drug
gene
target
acarbose
apolipoprotein a 1
lymphotoxin
0.8723
9 disease
gene
target
parkinson disease
apolipoprotein e
choline acetylase
0.8695
7 disease
drug
gene
gout
hydrochlorothiazide
endothelin 1
0.8357
11 disease
drug
gene
target
breast adenocarcinoma
tamoxifen
ppar-gamma
hmg-coa reductase
0.7826