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Table 7 Confirmation papers for the first new interaction predicted in 2005 for each subnetwork.

From: Can the vector space model be used to identify biological entity activities?

Subnetwork Dimensional Space First Interaction Confirmation Papers
1 disease × drug impotence
divalproex
[56, 57]
2 disease × gene acquired immunodeficiency syndrome
transforming growth factor, beta 1
[58, 59]
3 disease × target arrhythmia
cyclic-gmp phosphodiesterase
[60]
4 drug × gene ciclosporin
androgen receptor
[61, 62]
5 drug × target verapamil
cyclooxygenase 2
none
6 gene × target androgen receptor
adrenaline
[9]
7 disease × drug × gene gout
hydrochlorothiazide
endothelin 1
none
8 disease × drug × target alzheimer’s disease
aspirin
adrenaline
none
9 disease × gene × target parkinson’s disease
apolipoprotein e
choline acetylase
none
10 drug × gene × target acarbose
apolipoprotein a-1
lymphotoxin
none
11 disease × drug × gene × target breast cancer
tamoxifen
ppar-gamma
hmg-coa reductase
none