Skip to main content

Table 5 Upregulation of key target enzymes when H2 is produced under mixotrophic conditions, highlighted by AlgaGEM

From: AlgaGEM – a genome-scale metabolic reconstruction of algae based on the Chlamydomonas reinhardtii genome

Step reaction

Regulation (up/down)

Reference*

Cyclic electron flow (PSI)

-

[48]

Linear electron flow (PSII)

+

[48]

TCA cycle/mitochondria

-

[48]

Fe-Hydrogenases

+

[29, 31, 35, 49–52]

Ferredoxin-NADP+ reductase (FNR)

+

[53]

Glyceraldehyde 3-P-dehydrogenase

+

[54–57]

Pyruvate ferredoxin oxireductase

+

[58–60]

Calvin Cycle/CO2 assimilation

-

[44]

Acetate assimilation

+

[44]

Gluconeogenesis (cytosolic)

+

Not found

Pentose phosphate pathway (cytosolic)

-

Not found

Pentose phosphate pathway (plastidic)

+

Not found

Beta oxidation/glyoxylate cycle

-

Not found

glutamate synthase (ferredoxin);GSGOGAT

+

Not found

glutamine synthetase; GS/GOGAT

-

Not found

  1. *Results supported by evidences found in the literature. Not found: model highlights new targets in different pathways to improve H2 that need further experimental investigation for model validation.
Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us