Figure 4

A framework for adverse drug reaction prediction. Black arrows indicate data flows for ADR vs. drug target facts. Green arrows indicate data flows for ADR vs. drug target expanding network facts. (DrugBank: Drug-Target data; SIDER: Side Effect Resource; HAPPI: Human Annotated and Predicted Protein Interaction; GO: Gene Ontology; ADR: adverse drug reaction; SVM: support vector machine; Facts: multi-dimensional datasets)