Functional complementation between transcriptional methylation regulation and post-transcriptional microRNA regulation in the human genome

Table 2 Summary of microRNA target sites and methylation data in gene's promoter regions

Gene categories	Mean of microRNA target sites (gene number)	Mean of mCG/CG (gene number*)	Mean of CpG_O/E (gene number)	CGI number in promoter region (gene number)
Cancer genes	18.60 (379)	0.33 (381)	0.62 (381)	0.76 (412)
Dominant	19.18 (302)	0.33 (299)	0.61 (299)	0.73 (327)
Recessive	16.16 (76)	0.32 (80)	0.66 (80)	0.87 (84)
Others	14.34 (14,315)	0.53 (20,359)	0.48 (20,359)	0.53 (21,767)

CGI: CpG island. Dominant and Recessive genes are two major cancer gene categories.
*Those genes with CpG reads in their promoter region less than 3 were excluded.

ISSN: 1471-2164