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Table 2 Summary of microRNA target sites and methylation data in gene's promoter regions

From: Functional complementation between transcriptional methylation regulation and post-transcriptional microRNA regulation in the human genome

Gene categories Mean of microRNA target sites (gene number) Mean of mCG/CG (gene number*) Mean of CpGO/E (gene number) CGI number in promoter region (gene number)
Cancer genes 18.60 (379) 0.33 (381) 0.62 (381) 0.76 (412)
Dominant 19.18 (302) 0.33 (299) 0.61 (299) 0.73 (327)
Recessive 16.16 (76) 0.32 (80) 0.66 (80) 0.87 (84)
Others 14.34 (14,315) 0.53 (20,359) 0.48 (20,359) 0.53 (21,767)
  1. CGI: CpG island. Dominant and Recessive genes are two major cancer gene categories.
  2. *Those genes with CpG reads in their promoter region less than 3 were excluded.