Skip to main content

Table 2 Enrichment of genic and non-synonymous SNPs in genomic islands.

From: Evolutionary forces shaping genomic islands of population differentiation in humans

SNP subset Genic Non-synonymous
High population differentiation p-value(selection test) < = 0.01a 0.6576 0.1307
  Most likely states (Viterbi)b < 0.0001+ 0.0002+
  FDR < = 0.001c < 0.0001+ 0.0374+
  Islandsd < 0.0001+ 0.0053+
Low population differentiation p-value(selection test) < = 0.01a 0.2143 0.6402
  Most likely states (Viterbi)b 0.0303- 0.5888
  FDR < = 0.001c 0.0007- 0.6543
  Islandsd < 0.0001- 0.0083+
  1. Fisher exact test for enrichment or depletion of genic and non-synonymous SNPs in genomic islands defined by the selection test or by the HMM approach
  2. a subset of SNPs that are significant in the selection test at the 1% level
  3. b subset of SNPs that belong to the high-differentiation or low-differentiation state as identified by the Viterbi algorithm in the first step of the HMM approach
  4. c subset of SNPs that are assigned to the high-differentiation or low-differentiation state under a genome-wide FDR = 0.001 in the second step of the HMM approach
  5. d subset of SNPs that are located within HDIs or LDIs
  6. + enrichment of SNP category in SNP class
  7. - under-representation of SNP category in SNP class