Functional classifications of the Actinoplanes sp. SE50/110 protein coding sequences (CDS). The diagram represents the CDS that were categorized according their cluster of orthologous groups of proteins (COG) number [45, 51]. All depicted percentages refer to the distribution of 4999 annotated CDS (100%) across all COG categories to which at least 10 CDS were found. Sequences with an unknown or poorly characterized function were excluded from the analysis. These excluded CDS were found to be rather randomly distributed across the genome. The outer ring contains specialized subclasses of the three main functional categories "Cellular Processes and Signaling", "Metabolism", and "Information Storage and Processing", located at the center.