|
Transcription/Translation/RNA processing
| | | | |
1390
|
cAMP responsive element modulator
|
CREM
|
2.2
|
1.8
|
3.2
|
1958
|
early growth response 1
|
EGR1
|
1.9
|
2.0
|
1.7
|
22936
|
elongation factor, RNA polymerase II, 2
|
ELL2
|
2.2
|
2.2
|
2.2
|
2119
|
ets variant 5
|
ETV5
|
3.7
|
3.6
|
3.4
|
2353
|
FBJ murine osteosarcoma viral oncogene homolog
|
FOS
|
3.7
|
2.4
|
4.6
|
8061
|
FOS-like antigen 1
|
FOSL1
|
2.4
|
2.4
|
2.3
|
3280
|
Hairy and enhancer of split 1 (Drosophila)
|
HES1
|
1.8
|
1.9
|
2.0
|
3725
|
jun oncogene
|
JUN
|
4.7
|
5.9
|
5.3
|
10365
|
Kruppel-like factor 2 (lung)
|
KLF2
|
2.6
|
2.6
|
2.8
|
1316
|
Kruppel-like factor 6
|
KLF6
|
2.1
|
2.1
|
2.1
|
9935
|
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
|
MAFB
|
2.6
|
1.9
|
3.8
|
23764
|
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
|
MAFF
|
2.4
|
1.9
|
2.6
|
4929
|
nuclear receptor subfamily 4, group A, member 2
|
NR4A2
|
3.6
|
1.5
|
7.7
|
57157
|
Putative homeodomain transcription factor 2
|
PHTF2
|
1.9
|
1.9
|
2.0
|
6095
|
RAR-related orphan receptor A
|
RORA
|
10.3
|
2.0
|
10.6
|
7538
|
zinc finger protein 36, C3H type, homolog (mouse)
|
ZFP36
|
2.8
|
2.6
|
2.6
|
|
Signal Transduction
| | | | |
287
|
ankyrin 2, neuronal
|
ANK2
|
2.0
|
2.0
|
1.4
|
9518
|
growth differentiation factor 15
|
GDF15
|
5.0
|
4.9
|
5.6
|
2669
|
GTP binding protein over expressed in skeletal muscle
|
GEM
|
14.3
|
5.0
|
19.1
|
10681
|
guanine nucleotide binding protein (G protein), beta 5
|
GNB5
|
2.0
|
1.2
|
2.4
|
2786
|
guanine nucleotide binding protein (G protein), gamma 4
|
GNG4
|
1.8
|
2.0
|
1.6
|
26207
|
phosphatidylinositol transfer protein, cytoplasmic 1
|
PITPNC1
|
1.9
|
1.7
|
2.5
|
5329
|
plasminogen activator, urokinase receptor
|
PLAUR
|
2.0
|
1.7
|
1.9
|
5521
|
protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform
|
PPP2R2B
|
1.3
|
1.0
|
2.1
|
5997
|
regulator of G-protein signaling 2, 24 kDa
|
RGS2
|
2.4
|
1.1
|
2.4
|
6004
|
regulator of G-protein signaling 16
|
RGS16
|
2.0
|
2.0
|
2.0
|
6236
|
Ras-related associated with diabetes
|
RRAD
|
3.8
|
2.3
|
7.9
|
81848
|
sprouty homolog 4 (Drosophila)
|
SPRY4
|
1.9
|
2.1
|
1.9
|
|
Inflammatory response/Immune response
| | | | |
2921
|
chemokine (C-X-C motif) ligand 3
|
CXCL3
|
1.8
|
2.0
|
1.8
|
3269
|
histamine receptor H1
|
HRH1
|
2.5
|
1.7
|
1.8
|
7130
|
tumor necrosis factor, alpha-induced protein 6
|
TNFAIP6
|
20.5
|
1.3
|
36.6
|
|
Regulation of cell growth/Regulation of cell proliferation
| | | | |
183
|
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
|
AGT
|
1.3
|
1.3
|
2.3
|
374
|
amphiregulin
|
AREG
|
2.0
|
2.1
|
2.3
|
694
|
B-cell translocation gene 1, anti-proliferative
|
BTG1
|
3.3
|
1.1
|
3.0
|
6347
|
chemokine (C-C motif) ligand 2
|
CCL2
|
2.0
|
1.6
|
1.6
|
960
|
CD44 molecule (Indian blood group)
|
CD44
|
2.1
|
2.0
|
2.3
|
3491
|
cysteine-rich, angiogenic inducer, 61
|
CYR61
|
4.8
|
2.0
|
7.5
|
2014
|
epithelial membrane protein 3
|
EMP3
|
1.8
|
1.2
|
3.1
|
3589
|
interleukin 11
|
IL11
|
3.6
|
1.7
|
5.4
|
83729
|
inhibin, beta E
|
INHBE
|
2.1
|
3.0
|
1.9
|
182
|
jagged 1
|
JAG1
|
2.1
|
1.8
|
2.3
|
3976
|
leukemia inhibitory factor (cholinergic differentiation factor)
|
LIF
|
2.2
|
2.2
|
2.2
|
|
Apoptosis
| | | | |
56892
|
chromosome 8 open reading frame 4
|
C8orf4
|
1.2
|
1.2
|
2.3
|
8870
|
immediate early response 3
|
IER3
|
3.3
|
3.2
|
3.7
|
22822
|
pleckstrin homology-like domain, family A, member 1
|
PHLDA1
|
2.5
|
1.9
|
3.2
|
51330
|
tumor necrosis factor receptor superfamily, member 12A
|
TNFRSF12A
|
2.0
|
1.9
|
2.0
|
27242
|
tumor necrosis factor receptor superfamily, member 21
|
TNFRSF21
|
2.3
|
2.1
|
2.4
|
|
Cell adhesion/Cell-cell adhesion
| | | | |
6695
|
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
|
SPOCK1
|
2.0
|
1.7
|
2.1
|
6696
|
secreted phosphoprotein 1
|
SPP1
|
1.9
|
2.5
|
2.1
|
|
Transport
| | | | |
3039
|
hemoglobin, alpha 1
|
HBA1
|
2.4
|
2.5
|
2.4
|
4884
|
neuronal pentraxin I
|
NPTX1
|
2.3
|
1.2
|
3.6
|
6507
|
solute carrier family 1, member 3
|
SLC1A3
|
1.8
|
2.0
|
1.8
|
6533
|
solute carrier family 6, member 6
|
SLC6A6
|
2.2
|
2.3
|
1.9
|
23657
|
solute carrier family 7, member 11
|
SLC7A11
|
2.3
|
2.4
|
1.8
|
|
Metabolic process
| | | | |
384
|
arginase, type II
|
ARG2
|
3.2
|
3.2
|
3.6
|
9945
|
glutamine-fructose-6-phosphate transaminase 2
|
GFPT2
|
2.0
|
2.0
|
1.9
|
9388
|
Lipase, endothelial
|
LIPG
|
1.9
|
1.4
|
2.1
|
7378
|
uridine phosphorylase 1
|
UPP1
|
2.1
|
1.8
|
2.0
|
|
Phosphorylation/Dephosphorylation
| | | | |
9201
|
doublecortin-like kinase 1
|
DCLK1
|
2.1
|
2.0
|
2.1
|
1843
|
dual specificity phosphatase 1
|
DUSP1
|
3.6
|
2.4
|
4.7
|
51207
|
dual specificity phosphatase 13
|
DUSP13
|
2.2
|
1.9
|
2.2
|
1846
|
dual specificity phosphatase 4
|
DUSP4
|
2.9
|
3.0
|
2.9
|
1847
|
dual specificity phosphatase 5
|
DUSP5
|
2.4
|
2.4
|
2.8
|
1848
|
dual specificity phosphatase 6
|
DUSP6
|
2.4
|
2.8
|
2.7
|
5578
|
protein kinase C, alpha
|
PRKCA
|
2.1
|
1.9
|
1.8
|
|
Response to stress
| | | | |
3337
|
DnaJ (Hsp40) homolog, subfamily B, member 1
|
DNAJB1
|
2.7
|
3.1
|
2.5
|
3303
|
heat shock 70 kDa protein 1A
|
HSPA1A
|
2.9
|
4.2
|
2.8
|
3310
|
heat shock 70 kDa protein 6
|
HSPA6
|
6.4
|
15.4
|
5.3
|
|
Others/Unknown
| | | | |
202
|
absent in melanoma 1
|
AIM1
|
1.7
|
1.8
|
2.1
|
23237
|
activity-regulated cytoskeleton-associated protein
|
ARC
|
2.5
|
2.3
|
2.3
|
1475
|
cystatin A (stefin A)
|
CSTA
|
4.6
|
5.3
|
5.4
|
56603
|
cytochrome P450, family 26, subfamily B, polypeptide 1
|
CYP26B1
|
2.1
|
1.7
|
2.1
|
23052
|
endonuclease domain containing 1
|
ENDOD1
|
2.0
|
2.1
|
2.1
|
2201
|
fibrillin 2
|
FBN2
|
2.1
|
1.6
|
1.8
|
10324
|
kelch repeat and BTB (POZ) domain containing 10
|
KBTBD10
|
3.0
|
1.9
|
2.4
|
5270
|
serpin peptidase inhibitor, clade E, member 2
|
SERPINE2
|
2.3
|
2.3
|
2.4
|
4071
|
transmembrane 4 L six family member 1
|
TM4SF1
|
1.9
|
1.8
|
2.3
|
25907
|
transmembrane protein 158 (gene/pseudogene)
|
TMEM158
|
2.1
|
2.4
|
2.5
|
7171
|
tropomysin 4
|
TPM4
|
2.5
|
1.5
|
3.5
|
7846
|
tubulin, alpha 1a
|
TUBA1A
|
1.9
|
2.1
|
1.8
|