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Table 3 Ortholog analysis and classifications of the putative TCS proteins

From: A genome-wide study of two-component signal transduction systems in eight newly sequenced mutans streptococci strains

  TCSProtein RR family C1 C2 S. mutans
UA159
S. mutans
NN2025
S. mutans
5 DC8
S. mutans
KK21
S. mutans
KK23
S.mutans
AC4446
S. mutans
ATCC 25175
S. mutans
NCTC 11060
S.ratti
DSM20564
S. sobrinus
DSM20742
TCS-1 HK (VicK) - HPK1 C SMU.1516 GI|290580114 smc|01510 smd|01560 sme|01514 smf|01497 smg|01519 smh|01557 sra|1000270(90) sob|6900029(74)
  RR (VicR) OmpR -   SMU.1517 GI|290580113 smc|01511 smd|01561 sme|01515 smf|01498 smg|01520 smh|01558 sra|1000269(96) sob|6900028(87)
TCS-2 HK (CiaH) - HPK1 E SMU.1128 GI|290580439 smc|01121 smd|01170 sme|01262 smf|01137 smg|01147 smh|01166 sra|3300059(83) sob|10000005(53)
  RR (CiaR) OmpR -   SMU.1129 GI|290580438 smc|01122 smd|01171 sme|01263 smf|01138 smg|01148 smh|01167 sra|3300058(94) sob|10000006(86)
TCS-3 HK (CovS) - HPK1 E SMU.1145c GI|290580424 smc|01138 smd|01187 sme|01279 smf|01154 smg|01163 smh|01183 sra|3300038(48) Absent
  RR (CovR) OmpR -   SMU.1146c GI|290580423 smc|01139 smd|01188 sme|01280 smf|01155 smg|01164 smh|01184 sra|3300037(76) Absent
TCS-4 HK (KinF) - HPK1 E SMU.928 GI|290580625 smc|00919 smd|00964 sme|01045 smf|00943 smg|00948 smh|00938 sra|1200002(75) sob|15200007(50)
  RR (LlrF) OmpR -   SMU.927 GI|290580626 smc|00918 smd|00963 sme|01044 smf|00942 smg|00947 smh|00937 sra|1200003(89) sob|15200008(70)
TCS-5 HK (ScnK) - HPK1 E SMU.1814 GI|290579846 smc|01808 smd|01870 sme|01810 smf|01679 Absent Absent Absent Absent
  RR (ScnR) OmpR -   SMU.1815 GI|290579845 smc|01809 smd|01871 sme|01811 smf|01680 Absent Absent Absent Absent
TCS-6 HK (SpaK) - HPK1 E SMU.660 GI|290580857 smc|00645 smd|00684 sme|00777 smf|00640 smg|00672 smh|00668 sra|1000132(71) sob|3600002(47)
  RR (SpaR) OmpR -   SMU.659 GI|290580858 smc|00643 smd|00682 sme|00775 smf|00639 smg|00670 smh|00666 sra|1000130(80) sob|3600003(67)
TCS-7 HK (PhoR) - HPK1 E SMU.1037c GI|290580522 smc|01032 smd|01081 sme|01153 smf|01049 smg|01055 smh|01052 Absent Absent
  RR (YcbL) OmpR -   SMU.1038c GI|290580521 smc|01033 smd|01082 sme|01154 smf|01050 smg|01056 smh|01053 Absent Absent
TCS-8 HK (KinG) - HPK1 M SMU.1009 GI|290580539 smc|01005 smd|01053 sme|01135 smf|01030 smg|01036 smh|01024 sra|900051(80) sob|6900007(55)
  RR (LlrG) OmpR -   SMU.1008 GI|290580540 smc|01004 smd|01052 sme|01134 smf|01029 smg|01035 smh|01023 sra|900049(89) sob|6900006(64)
TCS-9 HK (LevS) - HPK7 M SMU.1965c GI|290579718 smc|01957 smd|02016 sme|01953 smf|01824 smg|01946 smh|01994 sra|3500035(88) Absent
  RR (LevR) NarL -   SMU.1964c GI|290579719 smc|01956 smd|02015 sme|01952 smf|01823 smg|01945 smh|01993 sra|3500036(91) Absent
TCS-10 HK (LytS) - HPK8 M SMU.577 GI|290580924 smc|00560 smd|00598 sme|00685 smf|00568 smg|00588 smh|00583 sra|1000030(95) sob|800016(80)
  RR (LytT) LytTR -   SMU.576 GI|290580925 smc|00559 smd|00597 sme|00684 smf|00567 smg|00587 smh|00582 sra|1000029(92) sob|800017(70)
TCS-11 HK (LiaS) - HPK7 M SMU.486 GI|290581011 smc|00465 smd|00505 sme|00595 smf|00473 smg|00493 smh|00475 sra|2900015(89) sob|4200072(64)
  RR (LiaR) NarL -   SMU.487 GI|290581010 smc|00466 smd|00506 sme|00596 smf|00474 smg|00494 smh|00476 sra|2900013(92) sob|4200071(82)
TCS-12 HK (HK11) - HPK7 M SMU.1548c GI|290580085 smc|01542 smd|01591 sme|01547 smf|01527 smg|01550 smh|01590 sra|1000231(53) sob|11300005(50)
  RR (RR11) NarL -   SMU.1547c GI|290580086 smc|01541 smd|01590 sme|01545 smf|01526 smg|01548 smh|01588 sra|1000232(82) sob|11300004(72)
TCS-13 HK(ComD) - HPK10 M SMU.1916 GI|290579761 smc|01910 smd|01968 sme|01906 smf|01777 smg|01900 smh|01947 Absent sob|8500005(37)
  RR (ComE) LytTR -   SMU.1917 GI|290579760 smc|01911 smd|01969 sme|01907 smf|01778 smg|01901 smh|01948 Absent sob|8500004(43)
TCS-14 HK - ? C SMU.45 GI|290579565 smc|00046 smd|00053 sme|00049 Absent Absent Absent Absent Absent
  RR ? -   SMU.46 GI|290579566 smc|00047 smd|00054 sme|00050 Absent Absent Absent Absent Absent
TCS-15 HK(ComP) - HPK7 M Absent Absent Absent Absent Absent Absent Absent smh|00177 Absent Absent
  RR(CmpR) NarL -   Absent Absent Absent Absent Absent Absent Absent smh|00178 Absent Absent
TCS-16 HK   HPK1 E Absent Absent Absent Absent Absent Absent Absent Absent sra|800020 Absent
  RR OmpR    Absent Absent Absent Absent Absent Absent Absent Absent sra|800019 Absent
TCS-17 HK   HPK1 E Absent Absent Absent Absent Absent Absent Absent Absent sra|3500015 Absent
  RR OmpR    Absent Absent Absent Absent Absent Absent Absent Absent sra|3500014 Absent
TCS-18 HK   HPK11 C Absent Absent Absent Absent Absent Absent Absent Absent sra|1400052 Absent
  RR AmiR    Absent Absent Absent Absent Absent Absent Absent Absent sra|1400053 Absent
Orphan HK1 HK   HPK1 N Absent Absent Absent Absent Absent Absent Absent Absent sra|3800008 Absent
Orphan HK2 HK   ? M Absent Absent Absent Absent Absent Absent Absent Absent Absent sob|13200014
Orphan RR1 RR (GcrR) OmpR -   SMU.1924 GI|290579753 smc|01920 smd|01978 sme|01916 smf|01787 smg|01910 smh|01957 sra|200007(87) sob|100018(55)
Orphan RR2   LytTR    Absent Absent Absent Absent Absent Absent Absent Absent Absent sob|14100005