Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes

Table 5 GO clustering analysis of upregulated genes in Manf^mzΔ96 mutants

	GO term	enrichment score	gene number
1	defense response, immune response	9.4	69
2	endopeptidase activity, proteolysis	6.4	197
...	peptidase inhibitor and enzyme inhibitor activity	4.0	24
...	stress response, response to abiotic stimulus	3.4	31
...	plasma membrane part, integral to plasma membrane	3.3	59
...	actin cytoskeleton organization	3.1	28
...	extracellular region part	2.8	30
...	cell death	2.7	28
...	embryonic and epithelial morphogenesis, cell polarity	2.5	67
...	cell adhesion	1.7	25
...	membrane invagination, phagocytosis, vesicle-mediated transport	1.6	50
...	apical junction, cell-cell junction assembly and organisation	1.6	22

Clusters are represented starting from the highest enrichment score in diminishing order. Only the highest clusters are shown, for the full list of DAVID cluster analysis of upregulated genes in Manf^mzΔ96 mutants, see Additional file 3. In the case on missing order number replaced by "..." there were several clusters higher in order describing similar processes that have been listed already above.

ISSN: 1471-2164