Table 3 Clustering of gene lists using functional annotations
From: Meta-analysis of Chicken – Salmonella infection experiments
Enrichment score (e) | Enrichment score (et) | (e)1 | (et)1 | (t-deduced)1 | Content Focus |
|---|---|---|---|---|---|
10.09 | 10.46 | 1 | 1 | 1 | Lumen of organelles, specifically the nucleus |
8.65 | 8.06 | 2 | 3 | 3 | ATP / nucleotide binding; phosphorylation, (ser, thr) kinase, transferase, S_TKc |
8.15 | 8.14 | 3 | 2 | 2 | Mitochondrion (outer and inner membranes) |
6.11 | 5.47 | 4 | 7 | 4-7 | SH3 protein domain |
5.94 | 6.30 | 5 | 5 | 5 | Mitochondrion |
5.31 | 5.93 | 6 | 6 | 6 | Macromolecules, specifically protein catabolism, including UBL mechanism |
5.00 | 6.42 | 7 | 4, 24 | 4-7, ± 20 | Macromolecules / protein transport, especially import in nucleus / localization |
4.83 | 4.28 | 8 | 8 | 8 | Non-membrane bound organelles and cytoskeleton |
4.31 | 3.95 | 9 | 10 | 9-10 | Cell cycle (process) |
4.12 | 3.57 | 10 | 13 | ±15 | actin cytoskeleton (binding) |
3.94 | 3.18 | 11 | 19 | ? | Protein folding / Chaperone protein |
3.90 | 3.85 | 12 | 11 | 11 | Angiogenesis |
3.73 | 3.69 | 13 | 12 | 12 | Ubl conjugation |
XXX | 3.56 | X | 14 | <10 | Tyrosine phosphorylation |
3.68 | 3.44 | 14 | 15 | 15 | Endoplasmic reticulum |
3.63 | XXX | 15 | X | X | Ubiquitin / proteasome proteolysis |
3.56 | 3.95 | 16 | 9 | 4-7 | Transcription |
3.52 | 3.22 | 17 | 17 | 17 | GTPase activity |
3.03 | 3.22 | 18 | 18 | 18 | Muscle morphology |
3.01 | XXX | 19 | X | X | Intracellular vesicles |
2.85 | 2.14 | 21 | 36 | ? | Cell-cell contacts |
2.82 | 2.98 | 22 | 20 | 20 | Protein modification and metabolism, including proteolysis |
2.75 | XXX | 23 | X | X | Protein domain WD (repeat) |
2.70 | 2.31 | 24 | 31 | ? | |
2.70 | 2.68 | 25 | 23 | 23 | Apoptosis |
2.69 | 2.72 | 26 | 22 | ±20 | RRM (RNA recognition motif) |
2.64 | 2.27 | 27 | 32 | ? | Macromolecule complexes, especially protein complexes |
2.45 | 2.07 | 31 | 38 | ±40 | Lysosome |
2.40 | XXX | 34 | X | X | Cell movement |
2.37 | 2.21 | 35 | 33 | 33 | Mitochondrion / organelle outer membrane |
2.21 | 1.67 | 36 | 52 | ? | Nucleotide binding via P-loop domain |
2.08 | 1.94 | 38 | 41 | 41 | Nuclear pore / RNA transport |
2.05 | 2.14 | 39 | 37 | 37 | Negative regulation of biosynthesis (nucleic acid, protein, macromolecules) |
2.05 | 2.04 | 40 | 39 | 39 | Cellular response to diverse stimuli |
1.03 | 2.2 - 1.55 | 126 | 35 + 61 | <40 | Muscle proteins, skeletal muscle morphology proteins |