Table 1 Main DNA binding motifs overrepresented in Pax8-dependent peaks
From: Genome-wide analysis of Pax8 binding provides new insights into thyroid functions
TF Matrices | Family information | Matches in Input (n) | Expected (genome) | Overrep. (genome) | Z-Score (genome) |
|---|---|---|---|---|---|
O$BRE.01 | Transcription factor II B (TFIIB) recognition element | 924 | 88.75 | 10.41 | 88.61 |
O$HMTE.01 | Human motif ten element | 2481 | 350.02 | 7.09 | 113.88 |
O$XCPE1.01 | X gene core promoter element 1 | 5454 | 1531.85 | 3.56 | 100.21 |
O$DMTE.01 | Drosophila motif ten element | 4415 | 1442.3 | 3.06 | 78.27 |
O$INR_DPE.01 | Initiator (INR) and downstream promoter element (DPE) with strictly maintained spacing | 2460 | 1071.16 | 2.30 | 42.42 |
V$NRF1.01 | Nuclear respiratory factor 1 | 6640 | 1323.52 | 5.02 | 146.13 |
V$SP1.02 | GC-Box factors SP1/GC; Stimulating protein 1, ubiquitous zinc finger transcription factor | 5792 | 1090.23 | 5.31 | 142.39 |
V$SP1.03 | GC-Box factors SP1/GC; Stimulating protein 1, ubiquitous zinc finger transcription factor | 4802 | 1129.17 | 5.14 | 139.05 |
V$ZF5.01 | Zinc finger / POZ domain transcription factor | 5543 | 1260.88 | 4.40 | 120.59 |
V$CTCF.01 | CCCTC-binding factor | 4729 | 1015.47 | 4.66 | 116.52 |